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ChemicalBook >> CAS DataBase List >>IWR-1-endo

IWR-1-endo suppliers

IWR-1-endo

CAS:
1127442-82-3
MF:
C25H19N3O3
MW:
409.44

Properties

alpha 
-3.0~+3.0°(20℃/D)(c=0.1,CH3CN)
Boiling point:
643.9±55.0 °C(Predicted)
Density 
1.425±0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
DMSO: soluble5mg/mL, clear
pka
11.88±0.43(Predicted)
form 
Liquid
color 
white to beige
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
Hazard statements 
H302
Precautionary statements 
P280-P305+P351+P338
WGK Germany 
3

Use

IWR-1-endo act as inhibitors of Wnt response. It appear that IWR compounds induce stabilization of Axin proteins via a direct interaction, which is a part of the b-catenin destruction complex (consists of Apc, Axin, Ck1 and Gsk3b). Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosi s.

1 supplier list of "IWR-1-endo"

  • Product Name:[(3aR*,4S*,7R*,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide
  • Products Intro:Package: 125USD/10mg;1000USD/100mg
  • Company Type: Trader
  • Country/Region: CANADA
You can find IWR-1-endo suppliers, manufacturers, and distributors from countries such as Canada here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

IWR-1-endo Related Search:

TYRPHOSTIN AG 879CantharidinTroglitazoneKY0211Y27632 (hydrochloride)XAV-939Wnt-C59CHIR-99021
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