trans-EKODE-(E)-Ib
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- $45 - $758
- Product name: trans-EKODE-(E)-Ib
- CAS: 478931-82-7
- MF: C18H30O4
- MW: 310.43
- EINECS:
- MDL Number:MFCD18427923
- Synonyms:trans-EKODE-(E)-Ib;trans-EKODE-(E)-Ib Exclusive;9-oxo-11-(3-pentyl-2-oxiranyl)-10(E)-undecenoic acid;12,13-epoxy-9-Oxo-10(E)-Octadecenoic Acid;10-Undecenoic acid, 9-oxo-11-(3-pentyl-2-oxiranyl)-, (10E)-
5 prices
Selected condition：
Brand
- Cayman Chemical
- TRC
Package
- 25μg
- 50μg
- 100μg
- 500μg
- ManufacturerCayman Chemical
- Product number10004224
- Product descriptiontrans-EKODE-(E)-Ib ≥98%
- Packaging25μg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10004224
- Product descriptiontrans-EKODE-(E)-Ib ≥98%
- Packaging50μg
- Price$92
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10004224
- Product descriptiontrans-EKODE-(E)-Ib ≥98%
- Packaging100μg
- Price$172
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10004224
- Product descriptiontrans-EKODE-(E)-Ib ≥98%
- Packaging500μg
- Price$758
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberE975108
- Product description(10E)-9-Oxo-11-(3-pentyl-2-oxiranyl)-10-undecenoicAcid
- Packaging25μg
- Price$45
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 10004224 | trans-EKODE-(E)-Ib ≥98% | 25μg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 10004224 | trans-EKODE-(E)-Ib ≥98% | 50μg | $92 | 2024-03-01 | Buy |
| Cayman Chemical | 10004224 | trans-EKODE-(E)-Ib ≥98% | 100μg | $172 | 2024-03-01 | Buy |
| Cayman Chemical | 10004224 | trans-EKODE-(E)-Ib ≥98% | 500μg | $758 | 2024-03-01 | Buy |
| TRC | E975108 | (10E)-9-Oxo-11-(3-pentyl-2-oxiranyl)-10-undecenoicAcid | 25μg | $45 | 2021-12-16 | Buy |
Properties
Boiling point :476.5±30.0 °C(Predicted)
Density :1.066±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): .5 mg/ml
pka :4.77±0.10(Predicted)
Density :1.066±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): .5 mg/ml
pka :4.77±0.10(Predicted)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||||
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Description
During oxidative stress, the abundant unsaturated fatty acid linoleic acid undergoes lipid peroxidation to produce α,β-unsaturated epoxy-keto-octadecenoic acids (EKODEs). Nonenzymatic autooxidation of linoleic acid generates six major EKODE isomers, which differ from one another in the positioning and the orientation of the epoxy group relative to the keto moiety. trans-EKODE-(E)-Ib is a biologically active peroxidation product of linoleic acid that is characterized, structurally, by having a trans carbon-carbon double bond between the 9-keto and 12,13-epoxy groups. It activates an antioxidant response element (ARE) in neuronal cells and induces the expression of ARE-regulated cytoprotective genes like NQO1. This EKODE also stimulates the synthesis of aldosterone and corticosterone in adrenal cells when supplied at 1-5 μM. This effect appears to be mediated by a rise in intracellular calcium.Suppliers and manufacturers
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