ICILIN
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- $42 - $1200
- Product name: ICILIN
- CAS: 36945-98-9
- MF: C16H13N3O4
- MW: 311.29
- EINECS:
- MDL Number:MFCD01689072
- Synonyms:ICILIN;3,6-DIHYDRO-1-(2-HYDROXYPHENYL)-4-(3-NITROPHENYL)-2(1H)-PYRIMIDINONE;AG-3-5;3,4-DIHYDRO-3-(2-HYDROXYPHENYL)-6-(3-NITROPHENYL)-(1H)-PYRIMIDIN-2-ONE;1-(2-HYDROXYPHENYL)-4-(3-NITROPHENYL)-1,2,3,6-TETRAHYDROPYRIMIDIN-2-ONE;1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-1,2,3,6-tetrahydropyrimidine-2-one ;3,6-dihydro-1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-2(1h)-pyrimidinon ;Iciline
31 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 5mg
- 10mg
- 25mg
- 50mg
- 50
- 100mg
- 250mg
- 500mg
- 10mM(in 1mL DMSO)
- 1g
- ManufacturerAK Scientific
- Product number1796AH
- Product descriptionICILIN
- Packaging1g
- Price$651
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA881912
- Product descriptionIcilin 97%
- Packaging10mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA881912
- Product descriptionIcilin 97%
- Packaging50mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1055
- Product descriptionIcilin
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1055
- Product descriptionIcilin
- Packaging10mg
- Price$62
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1055
- Product descriptionIcilin
- Packaging50mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS688093
- Product descriptionIcilin
- Packaging10mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546213
- Product descriptionIcilin >98%
- Packaging10mg
- Price$181.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546213
- Product descriptionIcilin >98%
- Packaging50mg
- Price$464.1
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBI164563
- Product descriptionIcilin
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBI164563
- Product descriptionIcilin
- Packaging50mg
- Price$246
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10137
- Product descriptionIcilin ≥98%
- Packaging5mg
- Price$50
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10137
- Product descriptionIcilin ≥98%
- Packaging10mg
- Price$84
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10137
- Product descriptionIcilin ≥98%
- Packaging50mg
- Price$376
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10137
- Product descriptionIcilin ≥98%
- Packaging100mg
- Price$545
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1922
- Product descriptionIcilin >96.0%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1796AH | ICILIN | 1g | $651 | 2021-12-16 | Buy |
| Ambeed | A881912 | Icilin 97% | 10mg | $42 | 2021-12-16 | Buy |
| Ambeed | A881912 | Icilin 97% | 50mg | $72 | 2021-12-16 | Buy |
| ApexBio Technology | B1055 | Icilin | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B1055 | Icilin | 10mg | $62 | 2021-12-16 | Buy |
| ApexBio Technology | B1055 | Icilin | 50mg | $238 | 2021-12-16 | Buy |
| Arctom | AS688093 | Icilin | 10mg | $42 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546213 | Icilin >98% | 10mg | $181.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546213 | Icilin >98% | 50mg | $464.1 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BI164563 | Icilin | 10mg | $70 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BI164563 | Icilin | 50mg | $246 | 2021-12-16 | Buy |
| Cayman Chemical | 10137 | Icilin ≥98% | 5mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 10137 | Icilin ≥98% | 10mg | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 10137 | Icilin ≥98% | 50mg | $376 | 2024-03-01 | Buy |
| Cayman Chemical | 10137 | Icilin ≥98% | 100mg | $545 | 2024-03-01 | Buy |
| ChemScene | CS-1922 | Icilin >96.0% | 10mg | $60 | 2021-12-16 | Buy |
Properties
Boiling point :594.8±50.0 °C(Predicted)
Density :1.415±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO: 15 mg/mL, soluble
form :solid
pka :9.94±0.35(Predicted)
color :yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :InChI=1S/C16H13N3O4/c20-15-7-2-1-6-14(15)18-9-8-13(17-16(18)21)11-4-3-5-12(10-11)19(22)23/h1-8,10,20H,9H2,(H,17,21)
InChIKey :RCEFMOGVOYEGJN-UHFFFAOYSA-N
SMILES :C1(=O)N(C2=CC=CC=C2O)CC=C(C2=CC=CC([N+]([O-])=O)=C2)N1
Density :1.415±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO: 15 mg/mL, soluble
form :solid
pka :9.94±0.35(Predicted)
color :yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :InChI=1S/C16H13N3O4/c20-15-7-2-1-6-14(15)18-9-8-13(17-16(18)21)11-4-3-5-12(10-11)19(22)23/h1-8,10,20H,9H2,(H,17,21)
InChIKey :RCEFMOGVOYEGJN-UHFFFAOYSA-N
SMILES :C1(=O)N(C2=CC=CC=C2O)CC=C(C2=CC=CC([N+]([O-])=O)=C2)N1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Nociceptive sensory peripheral neurons often express both heat sensitive (VR1) and cold-sensitive (CMR1 (rat); TRPM8 (human)) receptors that are part of the transient receptor potential (TRP) superfamily. Icilin (AG 3-5) is a synthetic CMR1/TRPM8 super agonist that is 2.5-fold more efficacious and nearly 200-fold more potent than the reference cold thermosensory agonist, l-menthol. Icilin induces sensations of intense cold when applied orally in humans, and induces 'wet dog shakes', a behavioral marker of cold sensation, when given to rats. Icilin should serve as the reference cold nociceptive agonist for TRP-type ion channels in the future.Related product price
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