Guanidine hydrochloride
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- $5 - $13385
- Product name: Guanidine hydrochloride
- CAS: 50-01-1
- MF: CH5N3.ClH
- MW: 95.53
- EINECS:200-002-3
- MDL Number:MFCD00013026
- Synonyms:guanidine,monohydrochloride ;guanidinechloride ;Guanidinemonohydrochloride ;AMINOFORMAMIDINE HCL;AMINOFORMAMIDINE HYDROCHLORIDE;AMINOMETHANAMIDINE HCL;AMINOMETHANAMIDINE HYDROCHLORIDE;Guanidine HCL（Low Ash)
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Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Aronis compounds
- ChemScene
- Matrix Scientific
- Medical Isotopes, Inc.
- Oakwood
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 20mg
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- 500mg
- 2.500g
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- 10g
- 25g
- 50g
- 100g
- 100ml
- 250g
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- 5Kg
- 10mM(in 1mL H2O)
- 10KG
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- 1KT
- 1KIT
- 10 kg
- 100 g
- ManufacturerAdipogen Life Sciences
- Product numberCDX-G0040-G100
- Product descriptionGuanidine hydrochloride ≥99%(Titration)
- Packaging100g
- Price$47
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberD014
- Product descriptionGuanidine hydrochloride
- Packaging500g
- Price$57
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA741759
- Product descriptionGuanidine hydrochloride 98+%
- Packaging25g
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA741759
- Product descriptionGuanidine hydrochloride 98+%
- Packaging100g
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA741759
- Product descriptionGuanidine hydrochloride 98+%
- Packaging500g
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA741759
- Product descriptionGuanidine hydrochloride 98+%
- Packaging1kg
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024811
- Product descriptionGUANIDINE HYDROCHLORIDE 99.00%
- Packaging1KG
- Price$330
- Updated2021-12-16
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- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024811
- Product descriptionGUANIDINE HYDROCHLORIDE 99.00%
- Packaging10KG
- Price$1050
- Updated2021-12-16
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- ManufacturerApexBio Technology
- Product numberB1949
- Product descriptionGuanidineHCl
- Packaging10g
- Price$42
- Updated2021-12-16
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- ManufacturerApexBio Technology
- Product numberB1949
- Product descriptionGuanidineHCl
- Packaging10mM(in 1mL H2O)
- Price$50
- Updated2021-12-16
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- ManufacturerApexBio Technology
- Product numberB1949
- Product descriptionGuanidineHCl
- Packaging50g
- Price$86
- Updated2021-12-16
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- ManufacturerApolloscientific
- Product numberBIMB2002
- Product descriptionGuanidine hydrochloride 99.5%
- Packaging500g
- Price$51
- Updated2021-12-16
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- ManufacturerApolloscientific
- Product numberBIMB2002
- Product descriptionGuanidine hydrochloride 99.5%
- Packaging1Kg
- Price$95
- Updated2021-12-16
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- ManufacturerApolloscientific
- Product numberBIMB2002
- Product descriptionGuanidine hydrochloride 99.5%
- Packaging5Kg
- Price$377
- Updated2021-12-16
- Buy
- ManufacturerAronis compounds
- Product numbere00716
- Product descriptionGuanidine hydrochloride
- Packaging20mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-2056
- Product descriptionGuanidine hydrochloride ≥98.0%
- Packaging500mg
- Price$50
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-G0040-G100 | Guanidine hydrochloride ≥99%(Titration) | 100g | $47 | 2021-12-16 | Buy |
| AK Scientific | D014 | Guanidine hydrochloride | 500g | $57 | 2021-12-16 | Buy |
| Ambeed | A741759 | Guanidine hydrochloride 98+% | 25g | $5 | 2021-12-16 | Buy |
| Ambeed | A741759 | Guanidine hydrochloride 98+% | 100g | $7 | 2021-12-16 | Buy |
| Ambeed | A741759 | Guanidine hydrochloride 98+% | 500g | $15 | 2021-12-16 | Buy |
| Ambeed | A741759 | Guanidine hydrochloride 98+% | 1kg | $28 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024811 | GUANIDINE HYDROCHLORIDE 99.00% | 1KG | $330 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024811 | GUANIDINE HYDROCHLORIDE 99.00% | 10KG | $1050 | 2021-12-16 | Buy |
| ApexBio Technology | B1949 | GuanidineHCl | 10g | $42 | 2021-12-16 | Buy |
| ApexBio Technology | B1949 | GuanidineHCl | 10mM(in 1mL H2O) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B1949 | GuanidineHCl | 50g | $86 | 2021-12-16 | Buy |
| Apolloscientific | BIMB2002 | Guanidine hydrochloride 99.5% | 500g | $51 | 2021-12-16 | Buy |
| Apolloscientific | BIMB2002 | Guanidine hydrochloride 99.5% | 1Kg | $95 | 2021-12-16 | Buy |
| Apolloscientific | BIMB2002 | Guanidine hydrochloride 99.5% | 5Kg | $377 | 2021-12-16 | Buy |
| Aronis compounds | e00716 | Guanidine hydrochloride | 20mg | $30 | 2021-12-16 | Buy |
| ChemScene | CS-2056 | Guanidine hydrochloride ≥98.0% | 500mg | $50 | 2021-12-16 | Buy |
Properties
Melting point :180-185 °C(lit.)
bulk density :550-620kg/m3
Density :1.18 g/mL at 25 °C(lit.)
refractive index :n20/D 1.465
storage temp. :room temp
solubility :H2O: 6 M, clear, colorless
form :Crystals
color :White to slightly yellow
Odor :Odorless
PH Range :4.5 - 6.0 at 573 g/l at 25 °C
PH :4.5-5.5 (100g/l, H2O, 20℃)
biological source :synthetic (organic)
Water Solubility :2280 g/L (20 ºC)
Sensitive :Hygroscopic
λmax :λ: 260 nm Amax: 0.040
λ: 280 nm Amax: 0.025 Merck :14,4562
BRN :3591990
Stability :Stable. Hygroscopic. Incompatible with strong oxidizing agents.
InChIKey :PJJJBBJSCAKJQF-UHFFFAOYSA-N
CAS DataBase Reference :50-01-1(CAS DataBase Reference)
EPA Substance Registry System :Guanidine monohydrochloride (50-01-1)
Absorption :≤0.10 at 260nm in H2O at 6M
bulk density :550-620kg/m3
Density :1.18 g/mL at 25 °C(lit.)
refractive index :n
storage temp. :room temp
solubility :H2O: 6 M, clear, colorless
form :Crystals
color :White to slightly yellow
Odor :Odorless
PH Range :4.5 - 6.0 at 573 g/l at 25 °C
PH :4.5-5.5 (100g/l, H2O, 20℃)
biological source :synthetic (organic)
Water Solubility :2280 g/L (20 ºC)
Sensitive :Hygroscopic
λmax :λ: 260 nm Amax: 0.040
λ: 280 nm Amax: 0.025 Merck :14,4562
BRN :3591990
Stability :Stable. Hygroscopic. Incompatible with strong oxidizing agents.
InChIKey :PJJJBBJSCAKJQF-UHFFFAOYSA-N
CAS DataBase Reference :50-01-1(CAS DataBase Reference)
EPA Substance Registry System :Guanidine monohydrochloride (50-01-1)
Absorption :≤0.10 at 260nm in H2O at 6M
Safety Information
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Description
Guanidine hydrochloride is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant.It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.Guanidine Hydrochloride is the hydrochloride salt form of guanidine, a strong basic compound with parasympathomimetic activity. Guanidine hydrochloride enhances the release of acetylcholine following a nerve impulse and potentiates acetylcholine actions on muscarinic and nicotinic receptors. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes.
Guanidine Hydrochloride is a powerful, chaotropic agent which is widely used for purification of proteins and nucleic acids. Guanidine Hydrochloride is useful for denaturation and refolding of proteins as well as in the recovery of periplasmic proteins and isolation of RNA. At higher concentrations, this strong denaturant has been reported to solubilize denatured insoluble proteins such as inclusion bodies. When utilized at lower concentrations, Guanidine Hydrochloride is noted to be useful in prompting the refolding of denatured proteins. Guanidine Hydrochloride is also been reported to allow return of enzymatic activity in protocols using Guanidine Hydrochloride as a first step. Guanidine Hydrochloride is an inhibitor of RNase.
Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized in the synthesis of 2-amino-pyrimidine, 2-amino-6-methyl-pyrimidine and 2-amino-4,6-dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.
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Suppliers and manufacturers
Dayang Chem (Hangzhou) Co.,Ltd.
Hefei TNJ Chemical Industry Co.,Ltd.
Qingdao Gangliwei Import & EXport Co.,Ltd
