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ChemicalBook >> CAS DataBase List >> Filgotinib

Filgotinib

Filgotinib price.
  • $25 - $7020
  • Product name: Filgotinib
  • CAS: 1206161-97-8
  • MF: C21H23N5O3S
  • MW: 425.5
  • EINECS:
  • MDL Number:MFCD20527867
  • Synonyms:GPLG0634;SYN1158;CyclopropanecarboxaMide, N-[5-[4-[(1,1-dioxido-4-thioMorpholinyl)Methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-;GLPG0634 (analog);N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-(5-(4-((1,1-Dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide;Filgotinib (GLPG0634);N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide Filgotinib (GLPG0634)
34 prices
Selected condition：
Brand
  • Abosyn
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 5g
  • 10g
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAbosyn
  • Product number61-11716
  • Product descriptionN-(5-(4-((1,1-Dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide 95-98%
  • Packaging1g
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1158-M050
  • Product descriptionGLPG0634 ≥95%
  • Packaging50mg
  • Price$1415
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2566AH
  • Product descriptionN-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-A]pyridin-2-yl)cyclopropanecarboxamide
  • Packaging10mg
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1130
  • Product descriptionGLPG0634
  • Packaging5mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1130
  • Product descriptionGLPG0634
  • Packaging10mM(in 1mL DMSO)
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1130
  • Product descriptionGLPG0634
  • Packaging25mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1130
  • Product descriptionGLPG0634
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0129
  • Product descriptionFilgotinib
  • Packaging5mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0129
  • Product descriptionFilgotinib
  • Packaging10mg
  • Price$176
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0129
  • Product descriptionFilgotinib
  • Packaging25mg
  • Price$284
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60409
  • Product descriptionFilgotinib(GLPG0634) ≥98%
  • Packaging10mg
  • Price$258
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBF159062
  • Product descriptionFilgotinib
  • Packaging25mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBF159062
  • Product descriptionFilgotinib
  • Packaging50mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBF159062
  • Product descriptionFilgotinib
  • Packaging100mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBF159062
  • Product descriptionFilgotinib
  • Packaging250mg
  • Price$205
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBF159062
  • Product descriptionFilgotinib
  • Packaging500mg
  • Price$325
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 61-11716 N-(5-(4-((1,1-Dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide 95-98% 1g $270 2021-12-16 Buy
Adipogen Life Sciences SYN-1158-M050 GLPG0634 ≥95% 50mg $1415 2021-12-16 Buy
AK Scientific 2566AH N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-A]pyridin-2-yl)cyclopropanecarboxamide 10mg $126 2021-12-16 Buy
ApexBio Technology B1130 GLPG0634 5mg $82 2021-12-16 Buy
ApexBio Technology B1130 GLPG0634 10mM(in 1mL DMSO) $110 2021-12-16 Buy
ApexBio Technology B1130 GLPG0634 25mg $180 2021-12-16 Buy
ApexBio Technology B1130 GLPG0634 100mg $600 2021-12-16 Buy
Apolloscientific BISN0129 Filgotinib 5mg $115 2021-12-16 Buy
Apolloscientific BISN0129 Filgotinib 10mg $176 2021-12-16 Buy
Apolloscientific BISN0129 Filgotinib 25mg $284 2021-12-16 Buy
Arctom CFN60409 Filgotinib(GLPG0634) ≥98% 10mg $258 2021-12-16 Buy
Biosynth Carbosynth BF159062 Filgotinib 25mg $60 2021-12-16 Buy
Biosynth Carbosynth BF159062 Filgotinib 50mg $90 2021-12-16 Buy
Biosynth Carbosynth BF159062 Filgotinib 100mg $132 2021-12-16 Buy
Biosynth Carbosynth BF159062 Filgotinib 250mg $205 2021-12-16 Buy
Biosynth Carbosynth BF159062 Filgotinib 500mg $325 2021-12-16 Buy

Properties

Melting point :229 - 231°C
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (15 mg/ml with warming)
form :solid
pka :8.04±0.20(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.

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