CEP-28122
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- $44 - $10725
- Product name: CEP-28122
- CAS: 1022958-60-6
- MF: C28H35ClN6O3
- MW: 539.07
- EINECS:200-258-5
- MDL Number:
- Synonyms:CEP-28122;(1S,2S,3R,4R)-3-[[5-Chloro-2-[[(7S)-6,7,8,9-tetrahydro-1-methoxy-7-(4-morpholinyl)-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-bicyclo[2.2.1]hept-5-ene-2-carboxamide;CS-1605;CEP 28122;CEP28122;(1S,2S,3R,4R)-3-[5-chloro-2-((S)-1-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-2-ylamino)pyrimidin-4-ylamino]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid amide;Bicyclo[2.2.1]hept-5-ene-2-carboxamide, 3-[[5-chloro-2-[[(7S)-6,7,8,9-tetrahydro-1-methoxy-7-(4-morpholinyl)-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-, (1S,2S,3R,4R)-;(1S,2S,3R,4R)-3-[(5-chloro-2-{[(7S)-1-methoxy-7-(morpholin-4-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}pyrimidin-4-yl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
13 prices
Selected condition：
Brand
- ApexBio Technology
- Cayman Chemical
- Chemenu
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerApexBio Technology
- Product numberC4025
- Product descriptionCEP-28122
- Packaging5mg
- Price$219
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4025
- Product descriptionCEP-28122
- Packaging10mg
- Price$389
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4025
- Product descriptionCEP-28122
- Packaging25mg
- Price$851
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18406
- Product descriptionCEP-28122 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18406
- Product descriptionCEP-28122 ≥98%
- Packaging5mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18406
- Product descriptionCEP-28122 ≥98%
- Packaging10mg
- Price$341
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18406
- Product descriptionCEP-28122 ≥98%
- Packaging25mg
- Price$745
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM155691
- Product description(1S,2S,4R)-3-((5-chloro-2-(((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide 98%
- Packaging100mg
- Price$355
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004814
- Product descriptionCEP-28122 98+%
- Packaging50mg
- Price$253
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004814
- Product descriptionCEP-28122 98+%
- Packaging100mg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8138
- Product descriptionCEP-28122 >98%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8138
- Product descriptionCEP-28122 >98%
- Packaging1g
- Price$2500
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC256650
- Product descriptionCEP-28122
- Packaging25mg
- Price$10725
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | C4025 | CEP-28122 | 5mg | $219 | 2021-12-16 | Buy |
| ApexBio Technology | C4025 | CEP-28122 | 10mg | $389 | 2021-12-16 | Buy |
| ApexBio Technology | C4025 | CEP-28122 | 25mg | $851 | 2021-12-16 | Buy |
| Cayman Chemical | 18406 | CEP-28122 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 18406 | CEP-28122 ≥98% | 5mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 18406 | CEP-28122 ≥98% | 10mg | $341 | 2024-03-01 | Buy |
| Cayman Chemical | 18406 | CEP-28122 ≥98% | 25mg | $745 | 2024-03-01 | Buy |
| Chemenu | CM155691 | (1S,2S,4R)-3-((5-chloro-2-(((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide 98% | 100mg | $355 | 2021-12-16 | Buy |
| Crysdot | CD31004814 | CEP-28122 98+% | 50mg | $253 | 2021-12-16 | Buy |
| Crysdot | CD31004814 | CEP-28122 98+% | 100mg | $380 | 2021-12-16 | Buy |
| DC Chemicals | DC8138 | CEP-28122 >98% | 100mg | $650 | 2021-12-16 | Buy |
| DC Chemicals | DC8138 | CEP-28122 >98% | 1g | $2500 | 2021-12-16 | Buy |
| TRC | C256650 | CEP-28122 | 25mg | $10725 | 2021-12-16 | Buy |
Properties
Boiling point :786.9±70.0 °C(Predicted)
Density :1.357±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤30mg/ml in DMSO;12mg/ml in dimethyl formamide
form :crystalline solid
pka :16.24±0.40(Predicted)
Density :1.357±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤30mg/ml in DMSO;12mg/ml in dimethyl formamide
form :crystalline solid
pka :16.24±0.40(Predicted)
Safety Information
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Description
CEP-28122 is a potent inhibitor of anaplastic lymphoma kinase (ALK; IC50 = 1.9 nM) that less potently inhibits other tyrosine and serine/threonine kinases. It blocks the phosphorylation of ALK and other ALK substrates in cells and induces concentration-dependent growth inhibition or cytotoxicity of ALK-positive cancer cells. CEP-28122 is orally active, inhibiting ALK tyrosine phosphorylation in tumor xenografts in mice for more than 12 hours following single oral dosing at 30 mg/kg.Related product price
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