18-HYDROXY-11-DEOXYCORTICOSTERONE
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- $75 - $679.14
- Product name: 18-HYDROXY-11-DEOXYCORTICOSTERONE
- CAS: 379-68-0
- MF: C21H30O4
- MW: 346.46
- EINECS:206-834-3
- MDL Number:MFCD00010486
- Synonyms:(8R,9S,10R,13R,14S,17S)-17-(2-hydroxyethanoyl)-13-(hydroxymethyl)-10-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one;(8R,9S,10R,13R,14S,17S)-17-glycoloyl-10-methyl-13-methylol-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one;11-DEOXY-18-HYDROXYCORTICOSTERONE;18-HYDROXY-11-DEOXYCORTICOSTERONE;18-HYDROXYDEOXYCORTICOSTERONE;18-HYDROXY DOC;18,20-EPOXY-20,21-DIHYDROXY-4-PREGNEN-3-ONE;18,21-DIHYDROXY-4-PREGNENE-3,20-DIONE
6 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- Sigma-Aldrich
- TRC
Package
- 500μg
- 1mg
- ManufacturerAK Scientific
- Product number3712CA
- Product description18,21-Dihydroxypregn-4-ene-3,20-dione
- Packaging1mg
- Price$293
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0006430
- Product description18-HYDROXY-11-DEOXYCORTICOSTERONE 95.00%
- Packaging1MG
- Price$679.14
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10007851
- Product description18-hydroxy-11-deoxy Corticosterone
- Packaging500μg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10007851
- Product description18-hydroxy-11-deoxy Corticosterone
- Packaging1mg
- Price$176
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberR200077
- Product description18,20-EPOXY-20,21-DIHYDROXYPREGN-4-EN-3-ONE AldrichCPR
- Packaging1MG
- Price$134
- Updated2023-06-20
- Buy
- ManufacturerTRC
- Product numberD239680
- Product description11-Deoxy-18-hydroxycorticosterone
- Packaging1mg
- Price$235
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 3712CA | 18,21-Dihydroxypregn-4-ene-3,20-dione | 1mg | $293 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0006430 | 18-HYDROXY-11-DEOXYCORTICOSTERONE 95.00% | 1MG | $679.14 | 2021-12-16 | Buy |
Cayman Chemical | 10007851 | 18-hydroxy-11-deoxy Corticosterone | 500μg | $75 | 2021-12-16 | Buy |
Cayman Chemical | 10007851 | 18-hydroxy-11-deoxy Corticosterone | 1mg | $176 | 2024-03-01 | Buy |
Sigma-Aldrich | R200077 | 18,20-EPOXY-20,21-DIHYDROXYPREGN-4-EN-3-ONE AldrichCPR | 1MG | $134 | 2023-06-20 | Buy |
TRC | D239680 | 11-Deoxy-18-hydroxycorticosterone | 1mg | $235 | 2021-12-16 | Buy |
Properties
Melting point :171-173 °C
storage temp. :2-8°C
solubility :Chloroform (Slightly, Sonicated), Methanol (Slightly, Heated)
form :Solid
color :White to Off-White
LogP :1.571 (est)
storage temp. :2-8°C
solubility :Chloroform (Slightly, Sonicated), Methanol (Slightly, Heated)
form :Solid
color :White to Off-White
LogP :1.571 (est)
Safety Information
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Description
18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland. Its biosynthesis is regulated by adrenocorticotropic hormone (ACTH; ) as well as angiotensin II , which increases 18-OH-DOC production in isolated human adrenal glomerulosa cells. 18-OH-DOC can be formed via conversion of 11-deoxy corticosterone (DOC; ) in human SK-MEL188 melanoma cells. 18-OH-DOC is an intermediate in the metabolism of progesterone and can be converted to aldosterone by the capsular portion of rat adrenal glands. Continuous infusion of 18-OH-DOC (200 μg/rat per day) increases systolic blood pressure in uninephrectomized saline-drinking rats. Plasma levels of 18-OH-DOC are elevated in a db/db mouse model of type 2 diabetes.More related product prices
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