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ChemicalBook >> CAS DataBase List >> 18-HYDROXY-11-DEOXYCORTICOSTERONE

18-HYDROXY-11-DEOXYCORTICOSTERONE

18-HYDROXY-11-DEOXYCORTICOSTERONE price.
  • $75 - $679.14
  • Product name: 18-HYDROXY-11-DEOXYCORTICOSTERONE
  • CAS: 379-68-0
  • MF: C21H30O4
  • MW: 346.46
  • EINECS:206-834-3
  • MDL Number:MFCD00010486
  • Synonyms:(8R,9S,10R,13R,14S,17S)-17-(2-hydroxyethanoyl)-13-(hydroxymethyl)-10-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one;(8R,9S,10R,13R,14S,17S)-17-glycoloyl-10-methyl-13-methylol-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one;11-DEOXY-18-HYDROXYCORTICOSTERONE;18-HYDROXY-11-DEOXYCORTICOSTERONE;18-HYDROXYDEOXYCORTICOSTERONE;18-HYDROXY DOC;18,20-EPOXY-20,21-DIHYDROXY-4-PREGNEN-3-ONE;18,21-DIHYDROXY-4-PREGNENE-3,20-DIONE
6 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 500μg
  • 1mg
  • ManufacturerAK Scientific
  • Product number3712CA
  • Product description18,21-Dihydroxypregn-4-ene-3,20-dione
  • Packaging1mg
  • Price$293
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0006430
  • Product description18-HYDROXY-11-DEOXYCORTICOSTERONE 95.00%
  • Packaging1MG
  • Price$679.14
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007851
  • Product description18-hydroxy-11-deoxy Corticosterone
  • Packaging500μg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007851
  • Product description18-hydroxy-11-deoxy Corticosterone
  • Packaging1mg
  • Price$176
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberR200077
  • Product description18,20-EPOXY-20,21-DIHYDROXYPREGN-4-EN-3-ONE AldrichCPR
  • Packaging1MG
  • Price$134
  • Updated2023-06-20
  • Buy
  • ManufacturerTRC
  • Product numberD239680
  • Product description11-Deoxy-18-hydroxycorticosterone
  • Packaging1mg
  • Price$235
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3712CA 18,21-Dihydroxypregn-4-ene-3,20-dione 1mg $293 2021-12-16 Buy
American Custom Chemicals Corporation CHM0006430 18-HYDROXY-11-DEOXYCORTICOSTERONE 95.00% 1MG $679.14 2021-12-16 Buy
Cayman Chemical 10007851 18-hydroxy-11-deoxy Corticosterone 500μg $75 2021-12-16 Buy
Cayman Chemical 10007851 18-hydroxy-11-deoxy Corticosterone 1mg $176 2024-03-01 Buy
Sigma-Aldrich R200077 18,20-EPOXY-20,21-DIHYDROXYPREGN-4-EN-3-ONE AldrichCPR 1MG $134 2023-06-20 Buy
TRC D239680 11-Deoxy-18-hydroxycorticosterone 1mg $235 2021-12-16 Buy

Properties

Melting point :171-173 °C
storage temp. :2-8°C
solubility :Chloroform (Slightly, Sonicated), Methanol (Slightly, Heated)
form :Solid
color :White to Off-White
LogP :1.571 (est)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland. Its biosynthesis is regulated by adrenocorticotropic hormone (ACTH; ) as well as angiotensin II , which increases 18-OH-DOC production in isolated human adrenal glomerulosa cells. 18-OH-DOC can be formed via conversion of 11-deoxy corticosterone (DOC; ) in human SK-MEL188 melanoma cells. 18-OH-DOC is an intermediate in the metabolism of progesterone and can be converted to aldosterone by the capsular portion of rat adrenal glands. Continuous infusion of 18-OH-DOC (200 μg/rat per day) increases systolic blood pressure in uninephrectomized saline-drinking rats. Plasma levels of 18-OH-DOC are elevated in a db/db mouse model of type 2 diabetes.

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