2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID
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- $32 - $1802
- Product name: 2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID
- CAS: 321674-73-1
- MF: C21H17NO3
- MW: 331.36
- EINECS:
- MDL Number:MFCD11112195
- Synonyms:2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID;BIBR 1532;2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl1-yl]amino]benzoicacid;2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl]amino]benzoic acid;(E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid;BIBR 1532, >=98%;BIBR 1532;BIBR-1532;CS-1061
30 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10
- 50
- 1MG
- 10mg
- 25mg
- 10mM(in 1mL DMSO)
- 50MG
- 100mg
- 250mg
- 1000mg
- 1g
- ManufacturerAK Scientific
- Product numberX7524
- Product description(E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoicacid
- Packaging10mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000875
- Product descriptionBIBR-1532 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000875
- Product descriptionBIBR-1532 95.00%
- Packaging10MG
- Price$709.46
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000875
- Product descriptionBIBR-1532 95.00%
- Packaging50MG
- Price$1267.33
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1945
- Product descriptionBIBR1532
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1945
- Product descriptionBIBR1532
- Packaging10mM(in 1mL DMSO)
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1945
- Product descriptionBIBR1532
- Packaging25mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1945
- Product descriptionBIBR1532
- Packaging100mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2301
- Product descriptionBIBR1532 99%
- Packaging5mg
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180843
- Product descriptionBIBR-1532 >98%
- Packaging100mg
- Price$606.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180843
- Product descriptionBIBR-1532 >98%
- Packaging250mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180843
- Product descriptionBIBR-1532 >98%
- Packaging1000mg
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16608
- Product descriptionBIBR 1532 ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16608
- Product descriptionBIBR 1532 ≥95%
- Packaging5mg
- Price$78
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16608
- Product descriptionBIBR 1532 ≥95%
- Packaging10mg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16608
- Product descriptionBIBR 1532 ≥95%
- Packaging50mg
- Price$517
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | X7524 | (E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoicacid | 10mg | $170 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000875 | BIBR-1532 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000875 | BIBR-1532 95.00% | 10MG | $709.46 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000875 | BIBR-1532 95.00% | 50MG | $1267.33 | 2021-12-16 | Buy |
ApexBio Technology | A1945 | BIBR1532 | 5mg | $50 | 2021-12-16 | Buy |
ApexBio Technology | A1945 | BIBR1532 | 10mM(in 1mL DMSO) | $99 | 2021-12-16 | Buy |
ApexBio Technology | A1945 | BIBR1532 | 25mg | $150 | 2021-12-16 | Buy |
ApexBio Technology | A1945 | BIBR1532 | 100mg | $400 | 2021-12-16 | Buy |
Axon Medchem | Axon2301 | BIBR1532 99% | 5mg | $77 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180843 | BIBR-1532 >98% | 100mg | $606.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180843 | BIBR-1532 >98% | 250mg | $912.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180843 | BIBR-1532 >98% | 1000mg | $1802 | 2021-12-16 | Buy |
Cayman Chemical | 16608 | BIBR 1532 ≥95% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 16608 | BIBR 1532 ≥95% | 5mg | $78 | 2024-03-01 | Buy |
Cayman Chemical | 16608 | BIBR 1532 ≥95% | 10mg | $120 | 2024-03-01 | Buy |
Cayman Chemical | 16608 | BIBR 1532 ≥95% | 50mg | $517 | 2024-03-01 | Buy |
Properties
Melting point :>173oC (dec.)
Boiling point :600.6±48.0 °C(Predicted)
Density :1.284
storage temp. :Store at RT
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
pka :3.46±0.36(Predicted)
form :Solid
color :White to Off-White
InChI :InChI=1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+
InChIKey :PGFQXGLPJUCTOI-WYMLVPIESA-N
SMILES :C(O)(=O)C1=CC=CC=C1NC(=O)/C=C(/C1=CC=C2C(=C1)C=CC=C2)\C
Boiling point :600.6±48.0 °C(Predicted)
Density :1.284
storage temp. :Store at RT
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
pka :3.46±0.36(Predicted)
form :Solid
color :White to Off-White
InChI :InChI=1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+
InChIKey :PGFQXGLPJUCTOI-WYMLVPIESA-N
SMILES :C(O)(=O)C1=CC=CC=C1NC(=O)/C=C(/C1=CC=C2C(=C1)C=CC=C2)\C
Safety Information
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Description
BIBR 1532 is a mixed-type non-competitive inhibitor of telomerase (IC50 = 93 nM) that has little effect on several mammalian DNA and RNA polymerases, bacterial DNA helicase, or HIV-1 reverse transcriptase. It specifically targets the telomerase reverse transcriptase catalytic subunit, TERT. Through its effects on telomerase, BIBR 1532 induces senescence or apoptosis in cancer cells. Apoptosis in triple negative breast cancer cells induced by BIBR 1532 is potentiated by glucose restriction.More related product prices
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Suppliers and manufacturers
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