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ChemicalBook >> CAS DataBase List >> 20-CARBOXY-LEUKOTRIENE B4

20-CARBOXY-LEUKOTRIENE B4

20-CARBOXY-LEUKOTRIENE B4 price.
  • $174 - $618
  • Product name: 20-CARBOXY-LEUKOTRIENE B4
  • CAS: 80434-82-8
  • MF: C20H30O6
  • MW: 366.45
  • EINECS:
  • MDL Number:MFCD00065857
  • Synonyms:20-CARBOXY-LEUKOTRIENE B4;20-COOH-LTB4;5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID;(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid;20-hydroxy-20-oxoleukotriene B4;6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)-;20-carboxy Leukotriene B4 (20-carboxy LTB4)
6 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 25μg
  • 50μg
  • 100μg
  • 5MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0001397
  • Product description20-CARBOXY-LEUKOTRIENE B4 97.00%
  • Packaging5MG
  • Price$500.23
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20180
  • Product description20-carboxy Leukotriene B4 ≥97%
  • Packaging25μg
  • Price$174
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20180
  • Product description20-carboxy Leukotriene B4 ≥97%
  • Packaging50μg
  • Price$328
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20180
  • Product description20-carboxy Leukotriene B4 ≥97%
  • Packaging100μg
  • Price$618
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC6046
  • Product description20-Carboxy-leukotriene B4 ~1?mg/mL in ethanol, ≥90% (HPLC)
  • Packaging25μg
  • Price$428
  • Updated2023-06-20
  • Buy
  • ManufacturerTRC
  • Product numberC724805
  • Product description20-COOH-LTB4
  • Packaging100μg
  • Price$540
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation LIP0001397 20-CARBOXY-LEUKOTRIENE B4 97.00% 5MG $500.23 2021-12-16 Buy
Cayman Chemical 20180 20-carboxy Leukotriene B4 ≥97% 25μg $174 2024-03-01 Buy
Cayman Chemical 20180 20-carboxy Leukotriene B4 ≥97% 50μg $328 2024-03-01 Buy
Cayman Chemical 20180 20-carboxy Leukotriene B4 ≥97% 100μg $618 2024-03-01 Buy
Sigma-Aldrich C6046 20-Carboxy-leukotriene B4 ~1?mg/mL in ethanol, ≥90% (HPLC) 25μg $428 2023-06-20 Buy
TRC C724805 20-COOH-LTB4 100μg $540 2021-12-16 Buy

Properties

Boiling point :588.3±50.0 °C(Predicted)
Density :1.151±0.06 g/cm3(Predicted)
Flash point :14℃
storage temp. :−20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
form :Liquid
pka :4.66±0.10(Predicted)
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. The resulting 20-hydroxy LTB4 is further oxidized to 20-carboxy LTB4. LTB4 metabolism in isolated rat hepatocytes also results in production of 20-carboxy LTB4 along with other ω-oxidation products. The biological activity of 20-carboxy LTB4 is only about 2.6% compared to that of LTB4 in causing PMNL degranulation.

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