5-(N,N-HEXAMETHYLENE)-AMILORIDE
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- $40 - $831.95
- Product name: 5-(N,N-HEXAMETHYLENE)-AMILORIDE
- CAS: 1428-95-1
- MF: C12H18ClN7O
- MW: 311.77
- EINECS:
- MDL Number:MFCD00069211
- Synonyms:5-(N,N-HEXAMETHYLENE)-AMILORIDE;AMILORIDE,5-(N,N-HEXAMETHYLENE)-;3-AMINO-N-(AMINOIMINOMETHYL)-6-CHLORO-5-(HEXAHYDRO-1H-AZEPIN-1-YL)-PYRAZINE-CARBOXAMIDE;AMILORIDE, 5-(N,N-HEXAMETHYLENE) >93% NA +/H+ ANTIPORTER INH;hma;amipromizide;3-Amino-5-(1-azacycloheptane-1-yl)-6-chloro-N-(aminoiminomethyl)pyrazine-2-carboxamide;3-Amino-5-(hexahydro-1H-azepin-1-yl)-6-chloro-N-(aminoiminomethyl)-2-pyrazinecarboxamide
12 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
Package
- 5mg
- 10mg
- 25MG
- 50mg
- 100MG
- ManufacturerAK Scientific
- Product number0066BA
- Product description5-(N,N-Hexamethylene)amiloride
- Packaging50mg
- Price$313
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000682
- Product description5-(N,N-HEXAMETHYLENE)-AMILORIDE 95.00%
- Packaging25MG
- Price$631.24
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000682
- Product description5-(N,N-HEXAMETHYLENE)-AMILORIDE 95.00%
- Packaging100MG
- Price$831.95
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29788
- Product description5-(N,N-hexamethylene)-Amiloride
- Packaging5mg
- Price$40
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29788
- Product description5-(N,N-hexamethylene)-Amiloride
- Packaging10mg
- Price$72
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29788
- Product description5-(N,N-hexamethylene)-Amiloride
- Packaging25mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29788
- Product description5-(N,N-hexamethylene)-Amiloride
- Packaging50mg
- Price$195
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29788
- Product description5-(N,N-hexamethylene)-Amiloride ≥98%
- Packaging100mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0095166
- Product description5-(N,N-Hexamethylene)-amiloride 98.42%
- Packaging10mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0095166
- Product description5-(N,N-Hexamethylene)-amiloride 98.42%
- Packaging50mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberA9561
- Product description5-(N,N-Hexamethylene)amiloride
- Packaging25mg
- Price$113
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberA9561
- Product description5-(N,N-Hexamethylene)amiloride
- Packaging100mg
- Price$151.2
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0066BA | 5-(N,N-Hexamethylene)amiloride | 50mg | $313 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000682 | 5-(N,N-HEXAMETHYLENE)-AMILORIDE 95.00% | 25MG | $631.24 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000682 | 5-(N,N-HEXAMETHYLENE)-AMILORIDE 95.00% | 100MG | $831.95 | 2021-12-16 | Buy |
| Cayman Chemical | 29788 | 5-(N,N-hexamethylene)-Amiloride | 5mg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 29788 | 5-(N,N-hexamethylene)-Amiloride | 10mg | $72 | 2024-03-01 | Buy |
| Cayman Chemical | 29788 | 5-(N,N-hexamethylene)-Amiloride | 25mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 29788 | 5-(N,N-hexamethylene)-Amiloride | 50mg | $195 | 2024-03-01 | Buy |
| Cayman Chemical | 29788 | 5-(N,N-hexamethylene)-Amiloride ≥98% | 100mg | $290 | 2021-12-16 | Buy |
| ChemScene | CS-0095166 | 5-(N,N-Hexamethylene)-amiloride 98.42% | 10mg | $80 | 2021-12-16 | Buy |
| ChemScene | CS-0095166 | 5-(N,N-Hexamethylene)-amiloride 98.42% | 50mg | $180 | 2021-12-16 | Buy |
| Sigma-Aldrich | A9561 | 5-(N,N-Hexamethylene)amiloride | 25mg | $113 | 2024-03-01 | Buy |
| Sigma-Aldrich | A9561 | 5-(N,N-Hexamethylene)amiloride | 100mg | $151.2 | 2024-03-01 | Buy |
Properties
Melting point :224-225 °C
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMF: 3mg/mL; DMSO: 10mg/mL; DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL
form :A crystalline solid
pka :8.81±0.46(Predicted)
color :Light yellow to yellow
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMF: 3mg/mL; DMSO: 10mg/mL; DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL
form :A crystalline solid
pka :8.81±0.46(Predicted)
color :Light yellow to yellow
Safety Information
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| Signal word: | Danger | ||||||||||
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Description
5-(N,N-hexamethylene)-Amiloride (HMA) is a derivative of amiloride with diverse biological activities. It is an allosteric antagonist of adenosine A2A receptors (Ki = 3.3 μM). HMA inhibits the cation-selective ion channel formed by the HIV-1 viral protein Vpu when used at a concentration of 50 μM, as well as budding of virus-like particles in HeLa cells expressing the HIV-1 proteins Gag and Vpu when used at a concentration of 10 μM. It also blocks the cation-selective ion channels formed by the hepatitis C virus (HCV) protein p7. HMA (40 μM) induces necrosis in and reduces the viability of MCF-7, MDA-MB-231, T47D, SK-BR-3, Met-1, and NDL breast cancer cells but not cardiomyocytes or uterine, pulmonary, and renal epithelial cells. HMA protects against post-ischemic contractile dysfunction and reduces coronary effluent creatine phosphokinase activity in a model of ischemia-reperfusion injury using isolated rat right ventricular free walls.Related product price
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