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ChemicalBook >> CAS DataBase List >> 1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester

1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester

1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester price.
  • $97 - $3025
  • Product name: 1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester
  • CAS: 1255666-48-8
  • MF: C10H18F2N2O2
  • MW: 236.26
  • EINECS:
  • MDL Number:MFCD16250242
  • Synonyms:4-Amino-3,3-difluoro-1-piperidinecarboxylic acid 1,1-dimethylethyl ester;1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester;4-AMino-1-Boc-3,3-difluor...;4-AMino-1-Boc-3,3-difluoropiperidine;tert-butyl 4-aMino-3,3-difluoropiperidine-1-carboxylate;1-N-Boc-4-amino-3,3-difluoro-piperidine;tert-butyl 4-amino-3,3-difluoropiperidin;1-Boc-4-amino-3,3-difluoropiperidine
17 prices
Selected condition：
Brand
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Chemenu
  • Matrix Scientific
  • SynQuest Laboratories
  • TRC
Package
  • 5MG
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 25g
  • ManufacturerAK Scientific
  • Product number4800AA
  • Product descriptiontert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate
  • Packaging5g
  • Price$1854
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1255666488
  • Product descriptiontert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate
  • Packaging5g
  • Price$998.13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164117
  • Product descriptiontert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+%
  • Packaging100mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164117
  • Product descriptiontert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+%
  • Packaging1g
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164117
  • Product descriptiontert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+%
  • Packaging250mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164117
  • Product descriptiontert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+%
  • Packaging5g
  • Price$357
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164117
  • Product descriptiontert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+%
  • Packaging25g
  • Price$1125
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0369948
  • Product descriptionTERT-BUTYL-4-AMINO-3,3-DIFLUOROPIPERIDINE-1-CARBOXYLATE 95.00%
  • Packaging5MG
  • Price$497.12
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC430297
  • Product descriptiontert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+%
  • Packaging250mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM106274
  • Product descriptiontert-butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95%
  • Packaging1g
  • Price$327
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM106274
  • Product descriptiontert-butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95%
  • Packaging5g
  • Price$982
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number097928
  • Product descriptiontert-Butyl 4-amino-3,3-difluoropiperidine-1-carboxylate 95+%
  • Packaging250mg
  • Price$1286
  • Updated2021-12-16
  • Buy
  • ManufacturerSynQuest Laboratories
  • Product number4H56-3-0A
  • Product description4-Amino-1-Boc-3,3-difluoropiperidine
  • Packaging250mg
  • Price$440
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB694060
  • Product description1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine
  • Packaging100mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB694060
  • Product description1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine
  • Packaging500mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB694060
  • Product description1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine
  • Packaging1g
  • Price$880
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4800AA tert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 5g $1854 2021-12-16 Buy
Alichem 1255666488 tert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 5g $998.13 2021-12-16 Buy
Ambeed A164117 tert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+% 100mg $97 2021-12-16 Buy
Ambeed A164117 tert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+% 1g $139 2021-12-16 Buy
Ambeed A164117 tert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+% 250mg $139 2021-12-16 Buy
Ambeed A164117 tert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+% 5g $357 2021-12-16 Buy
Ambeed A164117 tert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+% 25g $1125 2021-12-16 Buy
American Custom Chemicals Corporation HCH0369948 TERT-BUTYL-4-AMINO-3,3-DIFLUOROPIPERIDINE-1-CARBOXYLATE 95.00% 5MG $497.12 2021-12-16 Buy
Apolloscientific PC430297 tert-Butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95+% 250mg $111 2021-12-16 Buy
Chemenu CM106274 tert-butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95% 1g $327 2021-12-16 Buy
Chemenu CM106274 tert-butyl4-amino-3,3-difluoropiperidine-1-carboxylate 95% 5g $982 2021-12-16 Buy
Matrix Scientific 097928 tert-Butyl 4-amino-3,3-difluoropiperidine-1-carboxylate 95+% 250mg $1286 2021-12-16 Buy
SynQuest Laboratories 4H56-3-0A 4-Amino-1-Boc-3,3-difluoropiperidine 250mg $440 2021-12-16 Buy
TRC B694060 1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine 100mg $155 2021-12-16 Buy
TRC B694060 1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine 500mg $550 2021-12-16 Buy
TRC B694060 1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine 1g $880 2021-12-16 Buy

Properties

Boiling point :281.5±40.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
pka :7.66±0.40(Predicted)
Appearance :Off-white to yellow Solid
InChI :InChI=1S/C10H18F2N2O2/c1-9(2,3)16-8(15)14-5-4-7(13)10(11,12)6-14/h7H,4-6,13H2,1-3H3
InChIKey :APZOOTJWPGQYSZ-UHFFFAOYSA-N
SMILES :N1(C(OC(C)(C)C)=O)CCC(N)C(F)(F)C1

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine is synthetic building block for pharmaceuticals. It can be obtained from N-Benzyl-β-alanine Ethyl Ester (B232975) which is used as a reagent in organic synthesis including that of dipivaloyloxyphenyl aminopropionate β-agonist prodrugs which are used in the treatment of psoriasis. N-Benzyl-β-alanine Ethyl Ester (B232975) is also used in the synthesis of N,N'-dithiobis(N-benzyl-β-alanine) dethyl ester, which is an important intermediate of insecticide OK-135, and in synthesis of spiropiperidine-based orexin-2 receptor (OX2R) antagonists.