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?????? ??? ???
?? ??:
95-78-3
???:
??????
???(??):
2,5-????;P-????;??????;2,5-????,????,2,5-????-;2,5-??????
???:
2,5-Dimethylaniline
???(??):
2,5-XYLIDINE;ai3-16559;AKOS 91126;P-XYLIDINE;para-xylidine;2-amino-p-xylene;AKOS BBS-00003675;2-Amino-1,4-xylene;3,6-DIMETHYLANILINE;2,5-DIMETHYLANILINE
CBNumber:
CB9854710
???:
C8H11N
??? ??:
121.18
MOL ??:
95-78-3.mol
MSDS ??:
SDS

?????? ??

???
11.5 °C(lit.)
?? ?
218 °C(lit.)
??
0.973 g/mL at 25 °C(lit.)
???
20Pa
???
n20/D 1.559(lit.)
???
201 °F
?? ??
Store below +30°C.
???
Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Sparingly)
??? ??
??
?? ?? (pKa)
pK1:4.53(+1) (25°C)
??
??? ????? ?????
???
18°C?? <0.1g/100mL
Merck
14,10084
BRN
2205178
LogP
1.83
CAS ??????
95-78-3(CAS DataBase Reference)
IARC
3 (Vol. 16, Sup 7) 1987
NIST
Benzenamine, 2,5-dimethyl-(95-78-3)
EPA
2,5-Dimethylaniline (95-78-3)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? T,N,Xn
?? ???? ?? 23/24/25-33-51/53-48/20
????? 28-36/37-45-61-28A
????(UN No.) UN 1711 6.1/PG 2
WGK ?? 3
RTECS ?? ZE9100000
F ?????? 8-10-23
TSCA Yes
?? ?? 6.1
???? II
HS ?? 29214910
?? ?? ??? 95-78-3(Hazardous Substances Data)
????(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H373 ??? ?? ?? ???? ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ? ?? ?? ???? ?? - ?? ?? ?? 2 ?? P260, P314, P501
H411 ??? ??? ?? ????? ??? ?? ????? ?? - ?? ?? 2
??????:
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
P301+P310 ???? ?? ????(??)? ??? ????.
P314 ???? ??? ???? ??·??? ????.
NFPA 704
1
3 0

?????? MSDS


1-Amino-2,5-dimethylbenzene

?????? C??? ??, ??, ??

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clear yellow to red-brown liquid

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2,5-Dimethylaniline is widely used as raw materials to produce imaging chemicals like organic dyes and pigments. It is also used in the production of antioxidants, pharmaceutical, agricultural, rubber chemicals and other target organic molecules. 2,5-Dimethylaniline was also used in the synthesis of nanocomposite of multi-walled carbon nanotubes embedded in poly(2,5-dimethylaniline). 2,5-Dimethylaniline was used to study the effect of metabolites formed from 2,5-xylidine by fungi on laccase activity. The Fourier transform infrared (FTIR) and Raman spectra of 2,5-dimethylaniline was studied5. It induced transcription of lccIV.

??

ChEBI: A primary arylamine that is aniline in which the hydrogens at the 2- and 5-positions are replaced by methyl groups. It is used in the manufacture of dyes and other chemicals.

?? ??

Dark brown liquid.

??? ?? ??

2,5-Dimethylaniline may be sensitive to prolonged exposure to air. Insoluble in water.

?? ???

2,5-Dimethylaniline ignites on contact with fuming nitric acid . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

????

2,5-Dimethylaniline is combustible.

Safety Profile

Suspected carcinogen. A poison. Moderately toxic by ingestion. Quesuonable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also other xylidme entries.

Purification Methods

Convert p-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry over KOH and fractionally distil. The acetyl derivative has m 142o (from H2O or toluene), and the benzoyl derivative has m 140o (from EtOH). [Beilstein 12 H 1135, 12 IV 2567.]

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