チピラシル塩酸塩 価格 もっと(2)

メーカー	製品番號	製品説明	CAS番號	包裝	価格	更新時間	購入
Sigma-Aldrich Japan	SML1552	チピラシル 塩酸塩 ≥98% (HPLC) Tipiracil hydrochloride ≥98% (HPLC)	183204-72-0	10mg	￥24700	2024-03-01	購入
Sigma-Aldrich Japan	SML1552	チピラシル 塩酸塩 ≥98% (HPLC) Tipiracil hydrochloride ≥98% (HPLC)	183204-72-0	50mg	￥99700	2024-03-01	購入

チピラシル塩酸塩 化學(xué)特性,用途語,生産方法

効能

抗悪性腫瘍薬, 代謝拮抗薬

説明

Tipiracil (TPI) is a potent and competitive inhibitor of thymidine phosphorylase (TPase) with an IC₅₀ value of 35 nM for human placental TPase. It is selective for TPase over other pyrimidine-metabolizing enzymes (IC₅₀s = >1 mM for UPase, OPRTase, TK, and DPDase). TPI inhibits the phosphorolysis and degradation of trifluorothymidine , a cytotoxic nucleoside, in human breast and colon carcinoma tumor samples. Oral administration of TPI (12.5-50 mg/kg) enhances the anti-tumor activity of trifluorothymidine in a mouse AZ-521 stomach cancer xenograft model. Formulations containing TPI have been used for the treatment of metastatic colorectal cancer.

使用

Tipiracil Hydrochloride serves as a treatment for metastatic colorectal cancer (mCRC). A thymidine phosphorylase inhibitor.

定義

ChEBI: Tipiracil hydrochloride is a hydrochloride obtained by combining tipiracil with one equivalent of hydrochloric acid. Used in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer. It has a role as an antineoplastic agent and an EC 2.4.2.4 (thymidine phosphorylase) inhibitor. It is a hydrochloride and an iminium salt. It contains a tipiracil(1+).

チピラシル塩酸塩 上流と下流の製品情報

原材料

準(zhǔn)備製品

チピラシル塩酸塩 生産企業(yè)

名前	電話番號	電子メール	國籍	製品カタログ	優(yōu)位度
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Lianyungang happen teng technology co., LTD	15950718863	wang666xt@163.com	CHINA	295	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
Beijing Ribio Biotech Co.,Ltd	010-62664360 +8613328773880	wucy@ribio.com.cn	China	117	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
TargetMol Chemicals Inc.	+17819995354	marketing@targetmol.com	United States	32368	58

183204-72-0(チピラシル塩酸塩)キーワード:

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• 183204-72-0
• Tipiracil (hydrochloride)
• 2,4(1H,3H)-PyriMidinedione,5-chloro-6-[(2-iMino-1-pyrrolidinyl)Methyl] hydrochloride
• 5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione monohydrochloride
• Tipiracil HCl
• 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione,hydrochloride
• 5-Chloro-6-(2-iminopyrrolidin-1-ylmethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione hydrochloride
• 5-Chloro-6-(2-iminopyrrolidin-1-ylmethyl)uracil hydrochloride
• Tipiracil hydrochloride(TPI)
• Tipiracil-001-HCl
• CS-1684
• Tipiralacil
• Reaxys ID: 25670890
• Tipiracil-13C-15N2 HClTipiracil HCl
• 2,4(1H,3H)-Pyrimidinedione,5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-, hydrochloride (1:1)
• Tipiracil-13C-15N2 HCl
• 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione hydrochloride
• 5-Chloro-6-(2-iminopyrrolidin-1-ylmethyl)-1,2,3,4-tetrahydro...
• TAS-1-462
• Tibiracil Impurities 1
• Tipiracil Impurity 5 HCl
• Tipiracil Impurity 4 HCl
• Tipiracil hydrochloride【SML1552】
• チピラシル塩酸塩
• チピラシル塩酸塩 (JAN)
• 5-クロロ-6-(2-イミノピロリジン-1-イルメチル)ピリミジン-2,4(1H,3H)-ジオン
• 5-クロロ-6-[(2-イミノピロリジノ)メチル]ウラシル
• 5-クロロ-6-[(2-イミノピロリジン-1-イル)メチル]ピリミジン-2,4(1H,3H)-ジオン
• 5-クロロ-6-[(2-イミノピロリジン-1-イル)メチル]ウラシル
• 5-クロロ-6-[(2-イミノピロリジノ)メチル]ピリミジン-2,4(1H,3H)-ジオン
• 5-クロロ-6-[(2-イミノピロリジン-1-イル)メチル]-2,4(1H,3H)-ピリミジンジオン
• 5-クロロ-6-[(2-イミノピロリジン-1-イル)メチル]-1,2,3,4-テトラヒドロピリミジン-2,4-ジオン
• 5-クロロ-6-(2-イミノピロリジノメチル)ピリミジン-2(1H),4(3H)-ジオン
• 5-クロロ-6-(2-イミノピロリジノメチル)-1,2,3,4-テトラヒドロピリミジン-2,4-ジオン
• チピラシル