5-アミノ-2-ニトロ安息香酸
5-アミノ-2-ニトロ安息香酸 物理性質(zhì)
- 融點 :
- 236-238 °C (lit.)
- 沸點 :
- 481.3±35.0 °C(Predicted)
- 比重(密度) :
- 1.568±0.06 g/cm3(Predicted)
- 蒸気圧:
- 0-0Pa at 20-50℃
- 貯蔵溫度 :
- Keep in dark place,Inert atmosphere,Room temperature
- 溶解性:
- DMSO、メタノール
- 酸解離定數(shù)(Pka):
- 2.28±0.25(Predicted)
- 外見 :
- 個體
- 色:
- 黃褐色
- 水溶解度 :
- 不溶性
- BRN :
- 2107512
- InChIKey:
- KZZWQCKYLNIOBT-UHFFFAOYSA-N
- LogP:
- -1.48 at pH7
- 表面張力:
- 70.53mN/m at 1g/L and 20℃
- CAS データベース:
- 13280-60-9(CAS DataBase Reference)
5-アミノ-2-ニトロ安息香酸 価格
もっと(15)
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01COBOR-2751 |
5-アミノ-2-ニトロ安息香酸
5-Amino-2-nitrobenzoic acid |
13280-60-9 |
1g |
￥10000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01COBOR-2751 |
5-アミノ-2-ニトロ安息香酸
5-Amino-2-nitrobenzoic acid |
13280-60-9 |
5g |
￥14500 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01COBOR-2751 |
5-アミノ-2-ニトロ安息香酸
5-Amino-2-nitrobenzoic acid |
13280-60-9 |
25g |
￥50000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01COBOR-2751 |
5-Amino-2-nitrobenzoic acid |
13280-60-9 |
100g |
￥140000 |
2024-03-01 |
購入 |
|
東京化成工業(yè)
|
A0897 |
5-アミノ-2-ニトロ安息香酸 >98.0%(T)
5-Amino-2-nitrobenzoic Acid
>98.0%(T) |
13280-60-9 |
5g |
￥9700 |
2024-03-01 |
購入 |
5-アミノ-2-ニトロ安息香酸 化學(xué)特性,用途語,生産方法
外観
微黃色～黃色、結(jié)晶性粉末～粉末
用途
有機合成原料。
説明
5-Amino-2-nitrobenzoic acid is a reagent used in preparation of polymer-bound diazonium salts and insulin receptor tyrosine kinase activator. It is also used in 2-component dendritic chain reactions and activation of hydrophobic dendrimers.
化學(xué)的特性
5-Amino-2-nitrobenzoic acid appears as a yellow powder or crystal. Its crystal structure is: the 5-amino-2-nitrobenzoic acid crystallizes in the monoclinic P21/c
space group with a = 3.898(2)?, b = 13.531(3)?, c = 14.301(3) ?, and β = 90.83(3)?.
The adjacent molecules form a cyclic dimmer by intermolecular hydrogen bonds of type
O H···O with their carboxyl groups. In the crystal structure NH2 group forms a threecenter hydrogen bond with oxygen atoms of NO2 group.
使用
Reactant for:
- Two-component dendritic chain reactions
- Enzymic activation of hydrophobic self-immolative dendrimers
- Preparation of insulin receptor tyrosine kinase activator
- Preparation of polymer-bound diazonium salts using Merrifield resin-bound piperazine
主な応用
5-Amino-2-nitrobenzoic acid is a drug that has been shown to inhibit the activity of proteases. It has been used to detect the presence of protease activity in urine samples, as well as to study the inhibition of protease activity by other drugs. It is an inhibitor of chymotrypsin, trypsin, and elastase. This drug has been shown to be effective in inhibiting these enzymes at low concentrations, with a detection sensitivity of approximately 0.1 μM. It inhibits the growth of bacteria by binding to them and preventing protein synthesis. The compound also inhibits the enzyme dihydrolipoamide dehydrogenase in mitochondria, which is required for cellular respiration and energy production.
純化方法
Crystallise the acid from water. [Beilstein 14 III 1021.]
5-アミノ-2-ニトロ安息香酸 上流と下流の製品情報
原材料
準(zhǔn)備製品
5-アミノ-2-ニトロ安息香酸 生産企業(yè)
Global( 198)Suppliers
5-アミノ-2-ニトロ安息香酸 スペクトルデータ(1HNMR、IR1、IR2、MS)
13280-60-9(5-アミノ-2-ニトロ安息香酸)キーワード:
- 13280-60-9
- TIMTEC-BB SBB008583
- 5-AMINO-2-NITROBENZOIC ACID
- 3-AMINO-6-NITROBENZOIC ACID
- 3-CARBOXY-4-NITROANILINE
- ANBA
- 2-NITRO-5-AMINOBENZOIC ACID
- Benzoic acid, 5-amino-2-nitro-
- 5-AMINO-2-NITROBENZOIC ACID (PURIFIED)[FOR GAMMA-GT] 99+%
- 5-AMINO-2-NITROBENZOIC ACID 99+%
- 5-Amino-2-nitrobenzoic Acid (Purified) [for gamma-GT]
- 5-Amino-2-nitrobenzoic acid, 99 % (HPLC)
- 5-Amino-2-nitrobenzoic acid,97%
- 5-AMino-2-nitrobenzoic acid, 97% 1GR
- NSC 74455
- (Purified) [for gamma-GT]
- 5-Amino-2-nitrobenzoic Acid
- 5-Amino-2-nitrobenzoic Acid (Purified) [for &gamma
- 5-Amino-2-nitrobenzoic Acid (Purified) [for γ-GT]
- 5-Amino-2-nitrobenzoic Acid (Purified)[for γ-GT]>
- 5-Amino-2-nitrobenzoic Acid >
- 5-Amino-2-nitrobenzoicaci
- 5-Amino-2-nitrobenzoic acid USP/EP/BP
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- 5-アミノ-2-ニトロ安息香酸; 95%