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ChemicalBook >> CAS DataBase List >>3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, (4S)-

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, (4S)-

CAS No.
185197-71-1
Chemical Name:
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, (4S)-
Synonyms
(+)-Lercanidipine;Lercanidipine, (S)-;Lercanidipine Impurity 44;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, (4S)-
CBNumber:
CB98779459
Molecular Formula:
C36H41N3O6
Molecular Weight:
611.74
MDL Number:
MOL File:
185197-71-1.mol
Last updated:2025-04-18 09:53:11

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, (4S)- Properties

Boiling point 712.5±60.0 °C(Predicted)
Density 1.177±0.06 g/cm3(Predicted)
pka 8.66±0.50(Predicted)
FDA UNII J8GF8BXI8S

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, (4S)- Chemical Properties,Uses,Production

Uses

(S)-Lercanidipine is a calcium channel blocker with antihypertensive and neuroprotective activities. (S)-Lercanidipine reduces oxidative stress and protects auditory sensory hair cells from noise-induced damage. (S)-Lercanidipine showed significant protective effects on cell viability in in vitro experiments, especially at low concentrations. (S)-Lercanidipine has been found to effectively reduce the hearing threshold of mice after noise stimulation and protect the survival of outer hair cells. The antioxidant properties of (S)-Lercanidipine are reflected in its increased expression of antioxidant enzyme genes and decreased expression of oxidative enzyme genes. (S)-Lercanidipine administration is effective in reducing noise-induced hearing loss both before and after noise exposure. (S)-Lercanidipine may alleviate noise-induced hearing loss and protect the survival of outer hair cells through its antioxidant mechanism[1].

References

[1] Lercanidipine's Antioxidative Effect Prevents Noise-Induced Hearing Loss DOI:10.3390/antiox13030327

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, (4S)- Preparation Products And Raw materials

Raw materials

Preparation Products

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, (4S)- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 32351 58
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19927 58
QUALITY CONTROL SOLUTIONS LTD. 0755-66853366; 13670046396 ORDERS@QCSRM.COM China 24342 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 24803 58

View Lastest Price from 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, (4S)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lercanidipine, (S)- pictures 2024-11-19 Lercanidipine, (S)-
185197-71-1
US $2500.00-1520.00 / mg 10g TargetMol Chemicals Inc.
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, (4S)- (+)-Lercanidipine Lercanidipine, (S)- Lercanidipine Impurity 44 185197-71-1