Cetrorelix acetate
- CAS No.
- 130143-01-0
- Chemical Name:
- Cetrorelix acetate
- Synonyms
- SB-075 diacetate;NS-75A diacetate;Cetrelix Acetate;Cetrorenlin Acetate;Cetrorelix Diacetate;Cetrorelix diacetate, 10 mM in DMSO;Cetrorelix AcetateQ: What is Cetrorelix Acetate Q: What is the CAS Number of Cetrorelix Acetate;N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;(S)-N-((R)-1-Amino-1-oxopropan-2-yl)-1-((2S,5S,8R,11S,14S,17R,20R,23R)-20-(4-chlorobenzyl)-2-(3-guanidinopropyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-5-isobutyl-23-(naphthalen-2-ylmethyl)-4,7,10,13,16,19,22,25-octaoxo-17-(pyridin-3-ylmethyl)-8-(3-ureidopropyl)-3,6,9,12,15,18,21,24-octaazahexacosan-1-oyl)pyrrolidine-2-carboxamide diacetate
- CBNumber:
- CB9874701
- Molecular Formula:
- C70H92N17O14
- Molecular Weight:
- 1551.16
- MDL Number:
- MFCD00884467
- MOL File:
- 130143-01-0.mol
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
|---|---|
| solubility |
DMSO:50.0(Max Conc. mg/mL);33.53(Max Conc. mM) Water:2.0(Max Conc. mg/mL);1.34(Max Conc. mM) |
| Sequence | Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu- |
| CAS DataBase Reference | 130143-01-0(CAS DataBase Reference) |
| FDA UNII | W9Y8L7GP4C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Cetrorelix acetate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FC61440 | Cetrorelix acetate | 130143-01-0 | 10mg | $145 | 2021-12-16 | Buy |
| AK Scientific | V0412 | Cetrorelix acetate | 130143-01-0 | 5mg | $166 | 2021-12-16 | Buy |
| AK Scientific | V0412 | Cetrorelix acetate | 130143-01-0 | 10mg | $243 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC61440 | Cetrorelix acetate | 130143-01-0 | 50mg | $507.5 | 2021-12-16 | Buy |
| Ambeed | A206662 | Cetrorelixdiacetate 99+% | 130143-01-0 | 10mg | $552 | 2021-12-16 | Buy |
Cetrorelix acetate Chemical Properties,Uses,Production
Uses
Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM[1].
Clinical Use
Cetrorelix acetate is an analogue of GnRH with amino acid substitutions at residues 1, 2, 3, 6, and 10 and differing from ganirelix at amino acids 1, 6, and 8. Each of these substitutions are synthetic, non-DNA-directed amino acids and, like ganirelix acetate, impart GnRH antagonist activity to cetrorelix acetate. This drug also is marketed for use in women undergoing assisted reproductive therapy (ART) procedures, in which it is necessary to control their LH surge. This allows the follicles to develop to a size, as determined by ultrasound, that increases the success of timed insemination and oocyte retrieval for IVF. Like ganirelix acetate, cetrorelix acetate has an advantage over GnRH agonists, such as leuprolide acetate, because it reduces the fertility therapy cycle to days rather than weeks.
References
[1] Beckers T et al. Characterization of gonadotropin-releasing hormone analogs based on a sensitive cellular luciferase reporter gene assay. Anal Biochem. 1997 Aug 15;251(1):17-23. DOI:10.1006/abio.1997.2208
[2] Gründker C et al. Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer. Reprod Biol Endocrinol. 2003 Oct 7;1:65. DOI:10.1186/1477-7827-1-65
Cetrorelix acetate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Joiny Pharmaceutical Co.,LTD | +86-13681955282 +86-13681955282 | gyd@joiny-pharma.com | China | 258 | 58 |
| Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 924 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 10968 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29856 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Shochem(Shanghai) Co.,Ltd | 86-21-50800795 | info@shochem.com | CHINA | 288 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 995 | 58 |
View Lastest Price from Cetrorelix acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-04 | Cetrorelix acetate
130143-01-0
|
US $0.00 / g | 1g | 98%min | 1000g | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-06-03 | Cetrorelix diacetate
130143-01-0
|
US $50.00-500.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2025-04-28 | N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate
130143-01-0
|
US $0.00 / kg | 0.1kg | 98% | 200KG | Shanghai Joiny Pharmaceutical Co.,LTD |
-
- Cetrorelix acetate
130143-01-0
- US $0.00 / g
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Cetrorelix diacetate
130143-01-0
- US $50.00-500.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate
130143-01-0
- US $0.00 / kg
- 98%
- Shanghai Joiny Pharmaceutical Co.,LTD
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