1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1)
- CAS No.
- 1034687-52-9
- Chemical Name:
- 1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1)
- Synonyms
- GSK2018682 HCl;1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1)
- CBNumber:
- CB912850995
- Molecular Formula:
- C22H22Cl2N4O4
- Molecular Weight:
- 477.34
- MDL Number:
- MOL File:
- 1034687-52-9.mol
Last updated:2025-04-30 08:50:00
1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) Chemical Properties,Uses,Production
Uses
GSK2018682 hydrochloride is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4. GSK2018682 hydrochloride is used in the research of multiple sclerosis.
References
[1] Xu J, et al. Safety, pharmacokinetics, pharmacodynamics, and bioavailability of GSK2018682, a sphingosine-1-phosphate receptor modulator, in healthy volunteers. Clin Pharmacol Drug Dev. 2014 May;3(3):170-8. DOI:10.1002/cpdd.98
1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) Suppliers
Global( 2)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19931 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 25190 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
View Lastest Price from 1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-04-30 | GSK2018682 HCl
1034687-52-9
|
US $1520.00-2500.00 / mg | 10g | TargetMol Chemicals Inc. |
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- GSK2018682 HCl
1034687-52-9
- US $1520.00-2500.00 / mg
- TargetMol Chemicals Inc.
1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1)
GSK2018682 HCl
1034687-52-9