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1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1)

CAS No.
1034687-52-9
Chemical Name:
1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1)
Synonyms
GSK2018682 HCl;1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1)
CBNumber:
CB912850995
Molecular Formula:
C22H22Cl2N4O4
Molecular Weight:
477.34
MDL Number:
MOL File:
1034687-52-9.mol
Last updated:2025-04-30 08:50:00

1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) Chemical Properties,Uses,Production

Uses

GSK2018682 hydrochloride is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4. GSK2018682 hydrochloride is used in the research of multiple sclerosis.

References

[1] Xu J, et al. Safety, pharmacokinetics, pharmacodynamics, and bioavailability of GSK2018682, a sphingosine-1-phosphate receptor modulator, in healthy volunteers. Clin Pharmacol Drug Dev. 2014 May;3(3):170-8. DOI:10.1002/cpdd.98

1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19931 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 25190 58

View Lastest Price from 1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GSK2018682 HCl pictures 2025-04-30 GSK2018682 HCl
1034687-52-9
US $1520.00-2500.00 / mg 10g TargetMol Chemicals Inc.
  • GSK2018682 HCl pictures
  • GSK2018682 HCl
    1034687-52-9
  • US $1520.00-2500.00 / mg
  • TargetMol Chemicals Inc.
1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) GSK2018682 HCl 1034687-52-9