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ChemicalBook >> CAS DataBase List >>Ethanaminium, 2,2'-[1,2-diazenediylbis(4,1-phenyleneimino)]bis[N,N,N-triethyl-2-oxo-

Ethanaminium, 2,2'-[1,2-diazenediylbis(4,1-phenyleneimino)]bis[N,N,N-triethyl-2-oxo-

CAS No.
1204416-85-2
Chemical Name:
Ethanaminium, 2,2'-[1,2-diazenediylbis(4,1-phenyleneimino)]bis[N,N,N-triethyl-2-oxo-
Synonyms
Ethanaminium, 2,2'-[1,2-diazenediylbis(4,1-phenyleneimino)]bis[N,N,N-triethyl-2-oxo-
CBNumber:
CB910779612
Molecular Formula:
C28H44N6O2+2
Molecular Weight:
496.7
MDL Number:
MFCD30182303
MOL File:
1204416-85-2.mol
Last updated:2025-04-18 09:53:00

Ethanaminium, 2,2'-[1,2-diazenediylbis(4,1-phenyleneimino)]bis[N,N,N-triethyl-2-oxo- Chemical Properties,Uses,Production

Description

QAQ dichloride is a photoswitchable Nav, Cav, and Kv channel blocker, blocking channels in the trans form.

Uses

QAQ dichloride dichloride, a photoswitchable voltage-gated Nav and Kv channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain[1][2].

References

[1] Timm Fehrentz, et al. Exploring the Pharmacology and Action Spectra of Photochromic Open-Channel Blockers. Chembiochem. 2012 Aug 13;13(12):1746-9. DOI:10.1002/cbic.201200216
[2] Alexandre Mourot, et al.Photochromic Potassium Channel Blockers: Design and Electrophysiological Characterization. Methods Mol Biol. 2013;995:89-105. DOI:10.1007/978-1-62703-345-9_7

Ethanaminium, 2,2'-[1,2-diazenediylbis(4,1-phenyleneimino)]bis[N,N,N-triethyl-2-oxo- Preparation Products And Raw materials

Raw materials

Preparation Products

Ethanaminium, 2,2'-[1,2-diazenediylbis(4,1-phenyleneimino)]bis[N,N,N-triethyl-2-oxo- Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32282 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 20701 58
Ethanaminium, 2,2'-[1,2-diazenediylbis(4,1-phenyleneimino)]bis[N,N,N-triethyl-2-oxo- 1204416-85-2 C28H44N6O22