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ChemicalBook >> CAS DataBase List >>3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)

3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)

CAS No.
33985-68-1
Chemical Name:
3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)
Synonyms
C-DIM5;DIM-C-pPhOMe;DIM C pPhOMe;DIM-C-pPhOCH3;C-DIM5 ,S0149;DIM-C-pPhOCH3(C-DIM5);DIM-C-pPhOCH3 >=98% (HPLC);DIM-C-pPhOCH3, 10 mM in DMSO;Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane;1,1-bis(3′-Indolyl)-1-(p-methoxyphenyl)methane
CBNumber:
CB82682260
Molecular Formula:
C24H20N2O
Molecular Weight:
352.43
MDL Number:
MFCD01217840
MOL File:
33985-68-1.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24

3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Properties

Melting point 187-189 °C
Boiling point 592.7±50.0 °C(Predicted)
Density 1.251±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ≥30mg/mL
form powder
pka 16.63±0.30(Predicted)
color off-white to light yellow
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  3

3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D7946 DIM-C-pPhOCH3 ≥98% (HPLC) 33985-68-1 5mg $117 2025-07-31 Buy
Sigma-Aldrich D7946 DIM-C-pPhOCH3 ≥98% (HPLC) 33985-68-1 25mg $476 2025-07-31 Buy
Cayman Chemical 27980 C-DIM5 33985-68-1 5mg $105 2024-03-01 Buy
Cayman Chemical 27980 C-DIM5 33985-68-1 25mg $420 2024-03-01 Buy
Cayman Chemical 27980 C-DIM5 33985-68-1 1mg $32 2024-03-01 Buy
Product number Packaging Price Buy
D7946 5mg $117 Buy
D7946 25mg $476 Buy
27980 5mg $105 Buy
27980 25mg $420 Buy
27980 1mg $32 Buy

3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Chemical Properties,Uses,Production

Uses

[Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane, is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor.

Biological Activity

DIM-C-pPhOCH3 is a Nerve Growth Factor-Induced Bα (NGFI-Bα, Nur77) agonist

in vivo

DIM-C-pPhOCH3 (25 mg/kg/d) also inhibits tumor growth in athymic nude mice bearing RKO cell xenografts. The effects of DIM-C-pPhOCH3 (25 mg/kg/d) on colon tumor growth are also investigated in athymic nude mice bearing RKO cell xenografts. Treatment with the DIM-C-pPhOCH3 significantly decreases tumor volumes and final tumor weights compared with corn oil controls[1].

IC 50

Nur77/NR4A1

storage

Store at -20°C

3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 61)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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33985-68-1(3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole))Related Search:

DIM-C-pPhOCH3 3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) 1,1-bis(3′-Indolyl)-1-(p-methoxyphenyl)methane Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane DIM-C-pPhOCH3 >=98% (HPLC) 1H-Indole, 3,3'-[(4-methoxyphenyl)methylene]bis- DIM-C-pPhOCH3(C-DIM5) C-DIM5 Inhibitor,DIM-C-pPhOCH-3,DIM C pPhOCH3,DIMCpPhOCH3,inhibit DIM C pPhOMe DIM-C-pPhOMe DIM-C-pPhOCH3, 10 mM in DMSO C-DIM5 ,S0149 33985-68-1