3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)
- CAS No.
- 33985-68-1
- Chemical Name:
- 3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)
- Synonyms
- C-DIM5;DIM-C-pPhOMe;DIM C pPhOMe;DIM-C-pPhOCH3;C-DIM5 ,S0149;DIM-C-pPhOCH3(C-DIM5);DIM-C-pPhOCH3 >=98% (HPLC);DIM-C-pPhOCH3, 10 mM in DMSO;Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane;1,1-bis(3′-Indolyl)-1-(p-methoxyphenyl)methane
- CBNumber:
- CB82682260
- Molecular Formula:
- C24H20N2O
- Molecular Weight:
- 352.43
- MDL Number:
- MFCD01217840
- MOL File:
- 33985-68-1.mol
- MSDS File:
- SDS
Melting point | 187-189 °C |
---|---|
Boiling point | 592.7±50.0 °C(Predicted) |
Density | 1.251±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: ≥30mg/mL |
form | powder |
pka | 16.63±0.30(Predicted) |
color | off-white to light yellow |
UNSPSC Code | 12352200 |
NACRES | NA.77 |
3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) price More Price(22)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | D7946 | DIM-C-pPhOCH3 ≥98% (HPLC) | 33985-68-1 | 5mg | $117 | 2025-07-31 | Buy |
Sigma-Aldrich | D7946 | DIM-C-pPhOCH3 ≥98% (HPLC) | 33985-68-1 | 25mg | $476 | 2025-07-31 | Buy |
Cayman Chemical | 27980 | C-DIM5 | 33985-68-1 | 5mg | $105 | 2024-03-01 | Buy |
Cayman Chemical | 27980 | C-DIM5 | 33985-68-1 | 25mg | $420 | 2024-03-01 | Buy |
Cayman Chemical | 27980 | C-DIM5 | 33985-68-1 | 1mg | $32 | 2024-03-01 | Buy |
3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Chemical Properties,Uses,Production
Uses
[Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane, is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor.
Biological Activity
DIM-C-pPhOCH3 is a Nerve Growth Factor-Induced Bα (NGFI-Bα, Nur77) agonist
in vivo
DIM-C-pPhOCH3 (25 mg/kg/d) also inhibits tumor growth in athymic nude mice bearing RKO cell xenografts. The effects of DIM-C-pPhOCH3 (25 mg/kg/d) on colon tumor growth are also investigated in athymic nude mice bearing RKO cell xenografts. Treatment with the DIM-C-pPhOCH3 significantly decreases tumor volumes and final tumor weights compared with corn oil controls[1].
IC 50
Nur77/NR4A1
storage
Store at -20°C
3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38838 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
Shanghai Run-Biotech Co., Ltd. | 021-57171705 13817537615 | sales@run-biotech.com | China | 2294 | 58 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4648 | 55 | |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 7999 | 62 |