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ChemicalBook >> CAS DataBase List >>Benzenepropanoic acid, 4-[[2',6'-dimethyl-4'-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)oxy][1,1'-biphenyl]-3-yl]methoxy]-2-fluoro-

Benzenepropanoic acid, 4-[[2',6'-dimethyl-4'-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)oxy][1,1'-biphenyl]-3-yl]methoxy]-2-fluoro-

CAS No.
858097-86-6
Chemical Name:
Benzenepropanoic acid, 4-[[2',6'-dimethyl-4'-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)oxy][1,1'-biphenyl]-3-yl]methoxy]-2-fluoro-
Synonyms
TP-051;Benzenepropanoic acid, 4-[[2',6'-dimethyl-4'-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)oxy][1,1'-biphenyl]-3-yl]methoxy]-2-fluoro-
CBNumber:
CB812232725
Molecular Formula:
C29H31FO6S
Molecular Weight:
526.62
MDL Number:
MOL File:
858097-86-6.mol
Last updated:2025-04-28 21:36:36

Benzenepropanoic acid, 4-[[2',6'-dimethyl-4'-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)oxy][1,1'-biphenyl]-3-yl]methoxy]-2-fluoro- Properties

Boiling point 706.8±60.0 °C(Predicted)
Density 1.274±0.06 g/cm3(Predicted)
pka 4.70±0.10(Predicted)

Benzenepropanoic acid, 4-[[2',6'-dimethyl-4'-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)oxy][1,1'-biphenyl]-3-yl]methoxy]-2-fluoro- Chemical Properties,Uses,Production

Uses

TP-051 is a potent FFAR1 agonist with an Ki value of 16 nM for human FFAR1. TP-051 can increase insulin secretion in rat insulinoma cells. TP-051 can be used to research type 2 diabetes[1].

References

[1] Mikami S, et al. Discovery of phenylpropanoic acid derivatives containing polar functionalities as potent and orally bioavailable G protein-coupled receptor 40 agonists for the treatment of type 2 diabetes. J Med Chem. 2012 Apr 26;55(8):3756-76. DOI:10.1021/jm2016123

Benzenepropanoic acid, 4-[[2',6'-dimethyl-4'-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)oxy][1,1'-biphenyl]-3-yl]methoxy]-2-fluoro- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzenepropanoic acid, 4-[[2',6'-dimethyl-4'-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)oxy][1,1'-biphenyl]-3-yl]methoxy]-2-fluoro- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19925 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 24571 58

View Lastest Price from Benzenepropanoic acid, 4-[[2',6'-dimethyl-4'-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)oxy][1,1'-biphenyl]-3-yl]methoxy]-2-fluoro- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TP-051 pictures 2025-07-18 TP-051
858097-86-6
 US $2780.00-3700.00 / mg 10g TargetMol Chemicals Inc.
  • TP-051 pictures
  • TP-051
    858097-86-6
  • US $2780.00-3700.00 / mg
  • TargetMol Chemicals Inc.
Benzenepropanoic acid, 4-[[2',6'-dimethyl-4'-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)oxy][1,1'-biphenyl]-3-yl]methoxy]-2-fluoro- TP-051 858097-86-6 C29H31FO6S