4-Bromobenzocyclobutene
- CAS No.
- 1073-39-8
- Chemical Name:
- 4-Bromobenzocyclobutene
- Synonyms
- 3-bromobicyclo[4.2.0]octa-1(6),2,4-triene;4-Bromo-1,2-dihydrobenzocyclobutene;3-BROMO-BICYCLO[4.2.0]OCTA-1,3,5-TRIENE;4-Brombenzocyclobutene;4-bromocyclobutabenzene;4-Bromobenzocyclobutene;4-BROMO-BENZOCYCLOBUTANE;1-broMo-4-(cyclobut-1-en-1-yl)benzene;3-Bromobicyclo[4.2.]octa-1,3,5-triene;4-broMobicyclo[4.2.0]octa-1(6),2,4-triene
- CBNumber:
- CB7849617
- Molecular Formula:
- C8H7Br
- Molecular Weight:
- 183.05
- MDL Number:
- MFCD09029072
- MOL File:
- 1073-39-8.mol
- MSDS File:
- SDS
| Boiling point | 118-119 °C(Press: 20 Torr) |
|---|---|
| Density | 1.470 g/mL at 25 °C |
| refractive index | n20/D1.589 |
| Flash point | 100℃ |
| storage temp. | 2-8°C |
| form | liquid |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C8H7Br/c9-8-4-3-6-1-2-7(6)5-8/h3-5H,1-2H2 |
| InChIKey | GMHHTGYHERDNLO-UHFFFAOYSA-N |
| SMILES | C12C(CC1)=CC=C(Br)C=2 |
| CAS DataBase Reference | 1073-39-8(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-51 |
| WGK Germany | 3 |
4-Bromobenzocyclobutene price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 762121 | 4-Bromobenzocyclobutene 96% | 1073-39-8 | 1g | $122 | 2025-07-31 | Buy |
| TCI Chemical | B6357 | 3-Bromobicyclo[4.2.0]octa-1,3,5-triene min. 98.0 % | 1073-39-8 | 200MG | $32 | 2025-07-31 | Buy |
| TCI Chemical | B6357 | 3-Bromobicyclo[4.2.0]octa-1,3,5-triene min. 98.0 % | 1073-39-8 | 1G | $94 | 2025-07-31 | Buy |
| TRC | B680533 | 4-Bromobenzocyclobutene | 1073-39-8 | 250mg | $55 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB13826 | 4-Bromobenzocyclobutene | 1073-39-8 | 1g | $55 | 2021-12-16 | Buy |
4-Bromobenzocyclobutene Chemical Properties,Uses,Production
Chemical Properties
colorless or light yellow liquid
Synthesis
694-87-1
1073-39-8
The general procedure for the synthesis of 4-bromobenzocyclobutene from benzocyclobutene is as follows: first, α-chloro-o-xylene 1 is subjected to a pyrolysis reaction at about 800 °C and 0.5 mbar to produce benzocyclobutene 2 in 45% yield. Subsequently, benzocyclobutene 2 was dissolved in acetic acid and reacted with a mixture of bromine and iodine at room temperature for selective bromination to give 4-bromobenzocyclobutene 3. 3 was dissolved in toluene and a slightly molar excess of 1,4-dihydro-1,4-epoxynaphthalene 4 was added and reacted for 20 hr at 220° C. to give the Diels-Alder addition product 5 as a pure inner/outer in 80% yield mixture, which was a colorless crystalline substance. -yl)-5,12-dihydroanthracene 7. After recrystallization of compound 7 with o-dichlorobenzene, the dehydrogenation reaction was carried out by treatment with 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) in boiling o-xylene. After repeated vacuum sublimation purification, orange-red crystals of 2-(anthracen-2-yl)tetraphenyl 8 were finally obtained in 75% yield. All intermediates were characterized by 1H NMR, 13C NMR spectroscopy and mass spectrometry. Compound 8 was characterized by UV-visible spectroscopy.
References
[1] Chemistry - A European Journal, 2017, vol. 23, # 54, p. 13445 - 1345
[2] Patent: US2008/214838, 2008, A1. Location in patent: Page/Page column 2-3
[3] Tetrahedron, 1965, vol. 21, p. 245 - 254
[4] Journal of the Chemical Society [Section] B: Physical Organic, 1969, p. 12 - 15
[5] Patent: EP2236500, 2010, A1. Location in patent: Page/Page column 21
4-Bromobenzocyclobutene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20202 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from 4-Bromobenzocyclobutene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 4-Bromobenzocyclobutene
1073-39-8
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2023-12-26 | 4-Bromobenzocyclobutene
1073-39-8
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-08-08 | 4-Bromobenzocyclobutene
1073-39-8
|
US $150.00 / kg | 1kg | 99% | 1000tons | Henan Bao Enluo International TradeCo.，LTD |
-
- 4-Bromobenzocyclobutene
1073-39-8
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 4-Bromobenzocyclobutene
1073-39-8
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4-Bromobenzocyclobutene
1073-39-8
- US $150.00 / kg
- 99%
- Henan Bao Enluo International TradeCo.，LTD