(E)-cyclooct-4-enol / axial - TCO4 / A
- CAS No.
- 39637-78-0
- Chemical Name:
- (E)-cyclooct-4-enol / axial - TCO4 / A
- Synonyms
- (R)-TCO-OH;(R)-Cyclooct-4-en-1-ol;4-Cycloocten-1-ol, (1R)-;(E)-cyclooct-4-enol / axial - TCO / A;(E)-cyclooct-4-enol / axial - TCO4 / A
- CBNumber:
- CB75857181
- Molecular Formula:
- C8H14O
- Molecular Weight:
- 126.2
- MDL Number:
- MOL File:
- 39637-78-0.mol
(E)-cyclooct-4-enol / axial - TCO4 / A Chemical Properties,Uses,Production
Uses
(R)-TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. (R)-TCO-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
IC 50
Alkyl-Chain
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
(E)-cyclooct-4-enol / axial - TCO4 / A Preparation Products And Raw materials
Raw materials
Preparation Products
(E)-cyclooct-4-enol / axial - TCO4 / A Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32368 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| Changzhou Hopschain Chemical Co.,Ltd. | 0519-85528066 13775048983 | sales@hopschem.com | China | 31553 | 55 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29770 | 58 |
| Vicbio Biotechnology Co., Ltd. | 13691409741 | info@vicbio.com | China | 2127 | 58 |
| Beijing Famozi Pharmaceutical Technology Co., Ltd | 15811073878 | 2728639891@qq.com | China | 10015 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 176345344 7 17634854698 | 1959525201@qq.com | China | 10000 | 58 |