LSN 3213128 (LSN3213128)
- CAS No.
- 1941211-99-9
- Chemical Name:
- LSN 3213128 (LSN3213128)
- Synonyms
- LSN 3213128 (LSN3213128);2-Thiophenesulfonamide, N-(6-fluoro-1,2-dihydro-1-oxo-7-isoquinolinyl)-5-[(3R)-3-hydroxy-1-pyrrolidinyl]-
- CBNumber:
- CB74844995
- Molecular Formula:
- C17H16FN3O4S2
- Molecular Weight:
- 409.45
- MDL Number:
- MFCD32174255
- MOL File:
- 1941211-99-9.mol
LSN 3213128 (LSN3213128) Chemical Properties,Uses,Production
Uses
LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity[1].
References
[1] Fales KR, et al. Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransfera DOI:10.1021/acs.jmedchem.7b01046
LSN 3213128 (LSN3213128) Preparation Products And Raw materials
Raw materials
Preparation Products
LSN 3213128 (LSN3213128) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32376 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38838 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19939 | 58 |
Shanghai Beckham Medical Technology Co., Ltd | 021-13816613772 13816613772 | huahero21@sina.com | China | 1666 | 55 |
Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2380 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24982 | 58 |
View Lastest Price from LSN 3213128 (LSN3213128) manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-07-28 | LSN 3213128
1941211-99-9
|
US $2500.00-1430.00 / mg | 10g | TargetMol Chemicals Inc. | |||
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2025-07-21 | LSN 3213128
1941211-99-9
|
US $2500.00-1430.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- LSN 3213128
1941211-99-9
- US $2500.00-1430.00 / mg
- TargetMol Chemicals Inc.
-
- LSN 3213128
1941211-99-9
- US $2500.00-1430.00 / mg
- TargetMol Chemicals Inc.