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ChemicalBook >> CAS DataBase List >>Mcl1-IN-26

Mcl1-IN-26

CAS No.
2056238-04-9
Chemical Name:
Mcl1-IN-26
Synonyms
Mcl1-IN-26;1,17-Methano-1H-1,4,8,12,16-benzopentaazacycloheneicosine-3,7,15,24(2H,4H,6H)-tetrone, 5-[[4-chloro-3-(2-phenylethyl)phenyl]methyl]-5,8,9,10,11,12,13,14,16,17,18,19-dodecahydro-8-methyl-13-[[4-(methylsulfonyl)phenyl]methyl]-, (5R,13S,17S)-
CBNumber:
CB74668173
Molecular Formula:
C45H52ClN5O6S
Molecular Weight:
826.45
MDL Number:
MOL File:
2056238-04-9.mol
Last updated:2025-04-18 09:52:41

Mcl1-IN-26 Properties

Boiling point 1051.7±65.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
pka 13.90±0.60(Predicted)

Mcl1-IN-26 Chemical Properties,Uses,Production

Description

Mcl1-IN-26 is a potent and selective inhibitor of myeloid cell leukemia 1 (MCL1).

Uses

Mcl1-IN-5 (compound 21) is a MCL-1 inhibitor. Mcl1-IN-5 can be used for the research of cancers[1].

References

[1] Johannes JW, et al. Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors [published correction appears in ACS Med Chem Lett. 2017 Oct 18;8(11):1204]. ACS Med Chem Lett. 2016;8(2):239-244. DOI:10.1021/acsmedchemlett.6b00464

Mcl1-IN-26 Preparation Products And Raw materials

Raw materials

Preparation Products

Mcl1-IN-26 Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 32367 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 25433 58
Mcl1-IN-26 1,17-Methano-1H-1,4,8,12,16-benzopentaazacycloheneicosine-3,7,15,24(2H,4H,6H)-tetrone, 5-[[4-chloro-3-(2-phenylethyl)phenyl]methyl]-5,8,9,10,11,12,13,14,16,17,18,19-dodecahydro-8-methyl-13-[[4-(methylsulfonyl)phenyl]methyl]-, (5R,13S,17S)- 2056238-04-9