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ChemicalBook >> CAS DataBase List >>methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate

methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate

CAS No.
247037-81-6
Chemical Name:
methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
Synonyms
BAY395493;BAY39-5493;BAY 395493;BAY-395493;BAY 39-5493;BAY-39-5493;BAY395493,BAY39 5493;Ethyl (R)-4-(2-Chloro-4-fluorophenyl)-6-methyl-2-(2-thiazolyl)-1,4-dihydropyrimidine-5-carboxylate;(R)-ethyl 4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate;methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
CBNumber:
CB73384740
Molecular Formula:
C17H15ClFN3O2S
Molecular Weight:
379.84
MDL Number:
MOL File:
247037-81-6.mol
Last updated:2025-04-18 09:52:40

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alichem 247037816 Methyl(r)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate 247037-81-6 250mg $470.4 2021-12-16 Buy
Alichem 247037816 Methyl(r)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate 247037-81-6 1g $1308 2021-12-16 Buy
Product number Packaging Price Buy
247037816 250mg $470.4 Buy
247037816 1g $1308 Buy

methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate Chemical Properties,Uses,Production

Uses

BAY39-5493 is a non-nucleoside inhibitor that inhibits HBV replication. BAY39-5493 inhibits viral DNA replication by preventing the formation of viral core particles (nucleocapsids). The IC50 value of BAY39-5493 against HBV in stably transfected HepG2.2.15 cells is 0.03 μM[1].

References

[1] Deres K, et al. Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids[J]. Science, 2003, 299(5608): 893-896. DOI:10.1126/science.1077215

methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32376 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19939 58
Chengdu Focus Pharmaceutical Technology Co., Ltd. 028-64950838 17340131597 bd-focus@focuspharm.com China 875 58
TCI (Shanghai) Chemical Trading Co., Ltd. 021-61109150 sales@tcisct.com China 29668 58
Chengdu Dorher Pharmaceutical CO.,Ltd 19983537320 bd-focus@focuspharm.com China 1555 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24982 58
Shanghai Haohong Scientific Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39982 58

View Lastest Price from methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BAY39-5493 pictures 2024-10-24 BAY39-5493
247037-81-6
 US $2500.00-1520.00 / mg 10g TargetMol Chemicals Inc.
  • BAY39-5493 pictures
  • BAY39-5493
    247037-81-6
  • US $2500.00-1520.00 / mg
  • TargetMol Chemicals Inc.
Ethyl (R)-4-(2-Chloro-4-fluorophenyl)-6-methyl-2-(2-thiazolyl)-1,4-dihydropyrimidine-5-carboxylate methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (R)-ethyl 4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate 5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-1,4-dihydro-6-methyl-2-(2-thiazolyl)-, ethyl ester, (4R)- BAY 395493 BAY 39-5493 BAY395493 BAY-395493 BAY-39-5493 BAY39-5493 BAY395493,BAY39 5493 247037-81-6 C17H15ClFN3O2S