ChemicalBook >> CAS DataBase List >>RX-518
RX-518
- CAS No.
- 1660963-42-7
- Chemical Name:
- RX-518
- Synonyms
- CK101;CK 101;CK-101;RX-518;CS-2481;EGFR-IN-3;Olafertinib;RX518(CK-101);EGFR inhibitor 3;Olafertinib (RX-518)
- CBNumber:
- CB73119786
- Molecular Formula:
- C29H28F2N6O2
- Molecular Weight:
- 530.57
- MDL Number:
- MFCD30345533
- MOL File:
- 1660963-42-7.mol
Last updated:2025-07-19 12:08:47
| Density | 1.350±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMSO : 125 mg/mL (235.60 mM);Water : < 0.1 mg/mL (insoluble) |
| form | Solid |
| pka | 13.28±0.70(Predicted) |
| color | Light yellow to yellow |
| FDA UNII | 708TLB8J3Y |
RX-518 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0016788 | Olafertinib 99.94% | 1660963-42-7 | 5mg | $220 | 2021-12-16 | Buy |
| ChemScene | CS-0016788 | Olafertinib 99.94% | 1660963-42-7 | 10mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0016788 | Olafertinib 99.94% | 1660963-42-7 | 50mg | $900 | 2021-12-16 | Buy |
| ChemScene | CS-0016788 | Olafertinib 99.94% | 1660963-42-7 | 25mg | $650 | 2021-12-16 | Buy |
| ChemScene | CS-0016788 | Olafertinib 99.94% | 1660963-42-7 | 100mg | $1400 | 2021-12-16 | Buy |
RX-518 Chemical Properties,Uses,Production
Uses
Olafertinib is a third-generation EGFR TKI, with GI50 values of 5 nM (EGFR L858R/T790M), 10 nM (EGFR del19) and 689 nM (EGFR WT), respectively. Olafertinib has the potential for NSCLC research[1].
References
[1] Misako Nagasaka, et al. Beyond osimertinib: The development of 3 rd-generation EGFR Tyrosine Kinase Inhibitors. J Thorac Oncol. 2020 Dec 15;S1556-0864(20)31105-9. DOI:10.1016/j.jtho.2020.11.028
RX-518 Preparation Products And Raw materials
Raw materials
Preparation Products
RX-518 Suppliers
Global( 60)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32376 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9297 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38838 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Shanghai Hanhong Scientific Co., Ltd. | +undefined17612118332 | Lucky@hanhonggroup.com | China | 6035 | 58 |
View Lastest Price from RX-518 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-18 | EGFR-IN-3 | US $397.00-1580.00 / mg | 98.1% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-07-15 | Olafertinib
1660963-42-7
|
US $41.00-155.00 / mg | 98.43% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-04-04 | RX-518
1660963-42-7
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- EGFR-IN-3
- US $397.00-1580.00 / mg
- 98.1%
- TargetMol Chemicals Inc.
-
- Olafertinib
1660963-42-7
- US $41.00-155.00 / mg
- 98.43%
- TargetMol Chemicals Inc.
-
- RX-518
1660963-42-7
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
RX-518
N-(3-(2-((2,3-Difluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide
N-[3-[2-[2,3-difluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]quinazolin-8-yl]phenyl]prop-2-enamide
EGFR-IN-3
RX518(CK-101)
CK 101
CK101
CK-101
CK101;CK-101;CK 101;RX518;RX-518;RX 518
CS-2481
EGFR inhibitor 3
Olafertinib
2-Propenamide, N-[3-[2-[[2,3-difluoro-4-[4-(2-hydroxyethyl)-1-piperazinyl]phenyl]amino]-8-quinazolinyl]phenyl]-
Inhibitor,ErbB-1,Olafertinib,Epidermal growth factor receptor,NSCLC,HER1,EGFR,inhibit
RX518(CK-101:EGFR-IN-3)
Olafertinib (RX-518)
CK-101|||EGFR-IN-3|||RX-518
Olafertinib, 10 mM in DMSO
1660963-42-7
C29H28F2N6O2
