Acid-PEG5-mono-methyl ester
- CAS No.
- 1309460-30-7
- Chemical Name:
- Acid-PEG5-mono-methyl ester
- Synonyms
- COOH-PEG5-COOMe;COOH-PEG5-CH2CH2COOMe;Acid-PEG5-Methyl Ester;Acid-PEG5-mono-methyl ester;MeOOCCH2CH2O-PEG4-CH2CH2COOH;3-oxo-2,6,9,12,15,18-hexaoxahenicosan-21-oic acid;4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-methyl ester
- CBNumber:
- CB73062293
- Molecular Formula:
- C15H28O9
- Molecular Weight:
- 352.38
- MDL Number:
- MFCD18916990
- MOL File:
- 1309460-30-7.mol
| Boiling point | 469.4±45.0 °C(Predicted) |
|---|---|
| Density | 1.151±0.06 g/cm3(Predicted) |
| storage temp. | Storage temp. 2-8°C |
| solubility | Soluble in DCM |
| pka | 4.28±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
| InChI | InChI=1S/C15H28O9/c1-19-15(18)3-5-21-7-9-23-11-13-24-12-10-22-8-6-20-4-2-14(16)17/h2-13H2,1H3,(H,16,17) |
| InChIKey | LSGMOHWEFFVQEO-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)CCOCCOCCOCCOCCOCCC(O)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Acid-PEG5-mono-methyl ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C183735 | Carboxyl-PEG5-mono-methylEster | 1309460-30-7 | 5mg | $45 | 2021-12-16 | Buy |
| BroadPharm | BP-20440 | Acid-PEG5-mono-methylester 98% | 1309460-30-7 | 250mg | $540 | 2021-12-16 | Buy |
| BroadPharm | BP-20440 | Acid-PEG5-mono-methylester 98% | 1309460-30-7 | 500mg | $850 | 2021-12-16 | Buy |
Acid-PEG5-mono-methyl ester Chemical Properties,Uses,Production
Description
Acid-PEG5-mono-methyl ester is a PEG linker containing a terminal carboxylic acid and a mono-methyl ester functional group. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
Uses
Acid-PEG5-mono-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Acid-PEG5-mono-methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32376 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38838 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 2999 | 58 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6355 | 58 | |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28789 | 58 |
View Lastest Price from Acid-PEG5-mono-methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-19 | Acid-PEG5-mono-methyl ester
1309460-30-7
|
US $33.00-72.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | COOH-PEG5-COOMe
1309460-30-7
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Acid-PEG5-mono-methyl ester
1309460-30-7
- US $33.00-72.00 / mg
- TargetMol Chemicals Inc.
-
- COOH-PEG5-COOMe
1309460-30-7
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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