Propargyl-PEG5-NHS ester
- CAS No.
- 1393330-40-9
- Chemical Name:
- Propargyl-PEG5-NHS ester
- Synonyms
- Alkyne-PEG5-NHS;Propargyl-PEG4-Osu;Alkyne-PEG4-NHS Ester;Propargyl-PEG5-NHS ester;Propargyl-PEG4-CH2CH2COONHS;Propargyl-PEG4-C2-CONHS ester;Alkyne-PEG4-NHS Ester (CCT-TA103);4,7,10,13,16-Pentaoxanonadec-18-ynoic Acid N-Succinimidyl Ester;2,5-dioxopyrrolidin-1-yl 4,7,10,13,16-pentaoxanonadec-18-ynoate;2,5-Dioxopyrrolidin-1-yl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
- CBNumber:
- CB73049423
- Molecular Formula:
- C18H27NO9
- Molecular Weight:
- 401.41
- MDL Number:
- MFCD22574798
- MOL File:
- 1393330-40-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| HS Code | 2925.19.9100 | |||||||||
| NFPA 704 |
|
Propargyl-PEG5-NHS ester price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | P2283 | Propargyl-PEG5-NHS Ester | 1393330-40-9 | 25mg | $173 | 2024-03-01 | Buy |
| TRC | P839538 | Propargyl-PEG5-NHS Ester | 1393330-40-9 | 10mg | $65 | 2021-12-16 | Buy |
| Chem-Impex | 35117 | Alkyne-PEG4-NHSester,≥95%(HPLC) ≥95%(HPLC) | 1393330-40-9 | 5MG | $93.18 | 2021-12-16 | Buy |
| BroadPharm | BP-20907 | Propargyl-PEG5-NHS Ester 98% | 1393330-40-9 | 1g | $780 | 2021-12-16 | Buy |
| Chem-Impex | 35117 | Alkyne-PEG4-NHSester,95%(HPLC) 95%(HPLC) | 1393330-40-9 | 100MG | $985.6 | 2021-12-16 | Buy |
Propargyl-PEG5-NHS ester Chemical Properties,Uses,Production
Description
Propargyl-PEG5-NHS ester has a propargyl group and an NHS ester group. The terminal NHS ester and is an amine reactive moeity which is useful for derivatizing peptides, antibodies, amine coated surfaces etc. The propargyl group can participate in Click Chemistry reactions with azide compounds, copper is needed for catalyzation. The PEG units can enhance the hydrophilicity of the molecule.
Uses
Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Cleavable Linker; PEGs; Alkyl/ether
References
[1] Zhenjun Diwu, et al. Polyfluoreno[4,5-cde]oxepine Conjugates and Their Use in Methods of Analyte Detection. US20170275418A1.
Propargyl-PEG5-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5745 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32362 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38788 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from Propargyl-PEG5-NHS ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | Propargyl-PEG5-NHS ester
1393330-40-9
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. | |
 |
2024-10-24 | Propargyl-PEG5-NHS ester
1393330-40-9
|
US $0.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Propargyl-PEG5-NHS ester
1393330-40-9
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
-
- Propargyl-PEG5-NHS ester
1393330-40-9
- US $0.00 / mg
- TargetMol Chemicals Inc.
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