Neoenactin M1
- CAS No.
- 32886-15-0
- Chemical Name:
- Neoenactin M1
- Synonyms
- G-26146;Brn 2394950;Neoenactin M1;L-2-Amino-N-(14-methyl-3,10-dioxopentadecyl)hydracrylohydroxamic acid;(2S)-2-Amino-N,3-dihydroxy-N-(14-methyl-3,10-dioxopentadecyl)propanamide;Hydracrylohydroxamic acid, 2-amino-N-(14-methyl-3,10-dioxopentadecyl)-, L-;Propanamide, 2-amino-N,3-dihydroxy-N-(14-methyl-3,10-dioxopentadecyl)-, (S)-;Propanamide, 2-amino-N,3-dihydroxy-N-(14-methyl-3,10-dioxopentadecyl)-, (2S)-
- CBNumber:
- CB72327829
- Molecular Formula:
- C19H36N2O5
- Molecular Weight:
- 372.5
- MDL Number:
- MFCD01722759
- MOL File:
- 32886-15-0.mol
Boiling point | 578.1±60.0 °C(Predicted) |
---|---|
Density | 1.094±0.06 g/cm3(Predicted) |
pka | 8.46±0.50(Predicted) |
EWG's Food Scores | 1 |
Neoenactin M1 Chemical Properties,Uses,Production
Uses
Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM[1][2].
in vivo
Lipoxamycin is highly toxic in mice when applied subeutaneously or topically. Toxicity may be mechanism based, since studies with a Chinese hamster ovary cell mutant have shown that the serine palmitoyltransferase is an essential enzymein mammalian cells[1].
References
[1] S M Mandala, et al. Inhibition of Serine Palmitoyl-Transferase Activity by Lipoxamycin. J Antibiot (Tokyo). 1994 Mar;47(3):376-9. DOI:10.7164/antibiotics.47.376
[2] H A Whaley. The Structure of Lipoxamycin, a Novel Antifungal Antibiotic. J Am Chem Soc. 1971 Jul 28;93(15):3767-9. DOI:10.1021/ja00744a036
Neoenactin M1 Preparation Products And Raw materials
Raw materials
Preparation Products
Neoenactin M1 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32282 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38665 | 58 | |
Zhejiang Huida Biotech Co., LTD | 0571-89903882 15990081639 | sunshixuan@huidabiotech.com | China | 3644 | 58 |
Zhejiang Huida Biotech Co., LTD | 0571-0571-89903882 15990081639 | sunshixuan@huidabiotech.com | China | 3705 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 20701 | 58 |
View Lastest Price from Neoenactin M1 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-10-28 | Lipoxamycin
32886-15-0
|
US $2180.00-2800.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Lipoxamycin
32886-15-0
- US $2180.00-2800.00 / mg
- TargetMol Chemicals Inc.