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ChemicalBook >> CAS DataBase List >>6-amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile

6-amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile

CAS No.
663214-48-0
Chemical Name:
6-amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
Synonyms
WAY-324168;Antiproliferative agent-13;Antiproliferative agent-13, 10 mM in DMSO;6-amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile;8H-1,3-Dioxolo[4,5-g][1]benzopyran-7-carbonitrile, 6-amino-8-(3,4,5-trimethoxyphenyl)-;Inhibitor,cancer,antiproliferative,A375,Antiproliferative agent-13,Antiproliferative agent 13,WAY324168,inhibit,WAY 324168,microtubule inhibitor,Antiproliferative agent13
CBNumber:
CB63612013
Molecular Formula:
C20H18N2O6
Molecular Weight:
382.37
MDL Number:
MFCD04126993
MOL File:
663214-48-0.mol
Last updated:2025-07-16 16:28:12

6-amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile Properties

storage temp. Store at -20°C
solubility DMSO : 50 mg/mL (130.76 mM; ultrasonic and warming and heat to 60°C)
form Solid
color White to light yellow

6-amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile Chemical Properties,Uses,Production

Uses

Antiproliferative agent-13 (compound 16c) shows an antiproliferative activity against human A375 cells with an IC50 value of 32.7 nM. Antiproliferative agent-13 can be used for the research of cancer[1].

References

[1] Zhang H, et al. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities. Eur J Med Chem. 2018 Sep 5;157:380-396 DOI:10.1016/j.ejmech.2018.07.043

6-amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

6-amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32356 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38770 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Alinda Chemical Ltd. +7 (495) 672-17-08 sale@alinda.ru Russia 68136 55
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 6688 55
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4770 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62321 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24980 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 7325 58

View Lastest Price from 6-amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Antiproliferative agent-13 pictures 2025-07-16 Antiproliferative agent-13
663214-48-0
 US $48.00-173.00 / mg 98.36% 10g TargetMol Chemicals Inc.
6-amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile 8H-1,3-Dioxolo[4,5-g][1]benzopyran-7-carbonitrile, 6-amino-8-(3,4,5-trimethoxyphenyl)- WAY-324168 Inhibitor,cancer,antiproliferative,A375,Antiproliferative agent-13,Antiproliferative agent 13,WAY324168,inhibit,WAY 324168,microtubule inhibitor,Antiproliferative agent13 Antiproliferative agent-13 Antiproliferative agent-13, 10 mM in DMSO 663214-48-0