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ChemicalBook >> CAS DataBase List >>3-Hydroxytetrahydrofuran

3-Hydroxytetrahydrofuran

CAS No.
453-20-3
Chemical Name:
3-Hydroxytetrahydrofuran
Synonyms
Tetrahydrofuran-3-ol;3-Furanol, tetrahydro-;3-hydroxyoxolane;tetrahydro-3-furano;Tetrahydro-3-furanol;-Hydroxytetrahydrofuran;3-HYDROXYTETRAHYDROFURAN;3-HYDROXYTETRAHYDRAFURAN;3-Hydroxytetrahydrofurane;3-Hydroxytetrahydrofuran>
CBNumber:
CB6194228
Molecular Formula:
C4H8O2
Molecular Weight:
88.11
MDL Number:
MFCD00005374
MOL File:
453-20-3.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:48

3-Hydroxytetrahydrofuran Properties

Melting point 25°C
Boiling point 181 °C (lit.)
Density 1.09 g/mL at 25 °C (lit.)
vapor pressure 760 mm Hg ( 181 °C)
refractive index n20/D 1.45(lit.)
Flash point 178 °F
storage temp. Sealed in dry,Room Temperature
pka 14.49±0.20(Predicted)
form Liquid
color Clear colorless to yellow
Specific Gravity 1.090
Water Solubility 500g/L(room temperature)
Stability Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides.
InChIKey XDPCNPCKDGQBAN-UHFFFAOYSA-N
LogP -0.830 (est)
CAS DataBase Reference 453-20-3(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference Tetrahydrofuran, 3-hydroxy-(453-20-3)
EPA Substance Registry System 3-Furanol, tetrahydro- (453-20-3)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38-19
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  LU3450050
HS Code  29321900
NFPA 704
2
2 0

3-Hydroxytetrahydrofuran price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H59109 3-Hydroxytetrahydrofuran ReagentPlus , 98% 453-20-3 5g $18.9 2025-07-31 Buy
TCI Chemical H1331 3-Hydroxytetrahydrofuran >97.0%(GC) 453-20-3 5g $35 2025-07-31 Buy
TCI Chemical H1331 3-Hydroxytetrahydrofuran >97.0%(GC) 453-20-3 25g $138 2025-07-31 Buy
TRC H502205 3-Hydroxytetrahydrofuran 453-20-3 500mg $60 2021-12-16 Buy
AK Scientific P820 3-Hydroxytetrahydrofuran 453-20-3 25g $67 2021-12-16 Buy
Product number Packaging Price Buy
H59109 5g $18.9 Buy
H1331 5g $35 Buy
H1331 25g $138 Buy
H502205 500mg $60 Buy
P820 25g $67 Buy

3-Hydroxytetrahydrofuran Chemical Properties,Uses,Production

Chemical Properties

light yellow liquid

Synthesis

1,2,4-Butanetriol

3068-00-6

3-Hydroxytetrahydrofuran

453-20-3

The general procedure for the synthesis of 3-hydroxytetrahydrofuran from 1,2,4-butanetriol is as follows: 1,2,4-butanetriol is mixed with an equal volume of dioxane as a solvent in a batch reactor and a strongly acidic ion-exchange resin containing sulfonic acid groups (Amberlyst 15, in the H+ form) is added as a catalyst. The reaction was carried out at 100 °C for 20 h at atmospheric pressure. Upon completion of the reaction, the yield of 3-hydroxytetrahydrofuran was 96 mol%.

References

[1] Patent: WO2005/121111, 2005, A1. Location in patent: Page/Page column 33
[2] Patent: WO2005/121111, 2005, A1. Location in patent: Page/Page column 33
[3] Patent: WO2007/81065, 2007, A1. Location in patent: Page/Page column 6
[4] Patent: WO2005/121111, 2005, A1. Location in patent: Page/Page column 31; 34
[5] Patent: WO2005/121111, 2005, A1. Location in patent: Page/Page column 33-34

3068-00-6
453-20-3
Synthesis of 3-Hydroxytetrahydrofuran from 1,2,4-Butanetriol

3-Hydroxytetrahydrofuran Preparation Products And Raw materials

Global( 318)Suppliers
Supplier Tel Email Country ProdList Advantage
BTC Nantong Pharmaceuticals Technology Co.,Ltd
+8618068193575 sales4@btcpharm.com China 251 58
Wuhan Fortuna Chemical Co., Ltd 		+86-027-59207850 +86-13986145403; info@fortunachem.com China 5949 58
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29731 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21622 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Zjartschem 		+86-571 87238903 jocelynpan@zjarts.com CHINA 988 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29855 58
Zhejiang ZETian Fine Chemicals Co. LTD 		+8618957127338 stella@zetchem.com China 2136 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Jinan Shengqi pharmaceutical Co,Ltd 		86+18663751872 christine@shengqipharm.com CHINA 491 58

View Lastest Price from 3-Hydroxytetrahydrofuran manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Hydroxytetrahydrofuran pictures 2025-08-08 3-Hydroxytetrahydrofuran
453-20-3
 US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
3-Hydroxytetrahydrofuran pictures 2025-07-25 3-Hydroxytetrahydrofuran
453-20-3
 US $0.00 / kg 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
3-Hydroxytetrahydrofuran pictures 2025-04-04 3-Hydroxytetrahydrofuran
453-20-3
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
3-HYDROXYTETRAHYDROFURAN 3-hydroxyoxolane tetrahydro-3-furano Tetrahydro-3-furanol 3-HYDROXYTETRAHYDROFURAN 99% 3-Hydroxytetrahydrofurane 3-HYDROXYTETRAHYDRAFURAN 3-Hydroxytetrahydrofuran,97% 3-Hydroxytetrahydrofuran, 97% 25GR 3-Hydroxytetrahydrofuran, 97% 5GR 3-Hydroxytetrahydrofuran ReagentPlus(R), 98% 3-Hydroxytetrahydrofuran, 99%, 99% 3-Hydroxytetrahydrofuran Vetec(TM) reagent grade, 98% 3-Hydroxytetrahydrofuran> CAS No.453-20-3 3-Hydroxytetrahydrofuran 3-Furanol, tetrahydro- Tetrahydrofuran-3-ol -Hydroxytetrahydrofuran 453-20-3 864-44-7 453-30-3 C4H7O2 Heterocyclic Building Blocks Furans Building Blocks C4 to C7 Building Blocks Chemical Synthesis Heterocyclic Building Blocks Furans Building Blocks Heterocyclic Building Blocks Alcohols and Derivatives Heterocycles