2-Amino-5-nitrothiazole
- CAS No.
- 121-66-4
- Chemical Name:
- 2-Amino-5-nitrothiazole
- Synonyms
- 5-Nitrothiazol-2-amine;ENHEPTYNE;Nitazoxanide Related Compound A (25 mg) (2-Amino-5-nitrothiazole);NSC 4;ENHEPTIN;entramin;AKOS 203;ENTRAMINE;enheptint;enheptin-t
- CBNumber:
- CB5143401
- Molecular Formula:
- C3H3N3O2S
- Molecular Weight:
- 145.14
- MDL Number:
- MFCD00005326
- MOL File:
- 121-66-4.mol
- MSDS File:
- SDS
| Melting point | 195-200 °C (dec.) (lit.) |
|---|---|
| Boiling point | 345.1±15.0 °C(Predicted) |
| Density | 1.583 (estimate) |
| refractive index | 1.6740 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | 95% ethanol: soluble1g/150g at 20°C |
| form | Powder |
| pka | 1.26±0.10(Predicted) |
| color | Yellow |
| Water Solubility | <0.1 g/100 mL at 20 ºC |
| Sensitive | Light Sensitive |
| Merck | 14,457 |
| BRN | 126797 |
| Stability | Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides. |
| InChIKey | MIHADVKEHAFNPG-UHFFFAOYSA-N |
| Toxicology and Carcinogenesis | Bioassay of 2-Amino-5-Nitrothiazole for Possible Carcinogenicity (CASRN 121-66-4) |
| CAS DataBase Reference | 121-66-4(CAS DataBase Reference) |
| FDA UNII | 1GR77A37Z5 |
| IARC | 3 (Vol. 31, Sup 7) 1987 |
| EPA Substance Registry System | 2-Amino-5-nitrothiazole (121-66-4) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XJ2800000 | |||||||||
| F | 8 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29341000 | |||||||||
| Hazardous Substances Data | 121-66-4(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
2-Amino-5-nitrothiazole price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2889 | Nitazoxanide Related Compound A pharmaceutical secondary standard, certified reference material | 121-66-4 | 50MG | $557 | 2025-07-31 | Buy |
| Sigma-Aldrich | 133507 | 2-Amino-5-nitrothiazole 97% | 121-66-4 | 25g | $42.65 | 2025-07-31 | Buy |
| Sigma-Aldrich | 133507 | 2-Amino-5-nitrothiazole 97% | 121-66-4 | 100g | $160 | 2025-07-31 | Buy |
| TCI Chemical | A0381 | 2-Amino-5-nitrothiazole >98.0%(HPLC)(T) | 121-66-4 | 25g | $100 | 2025-07-31 | Buy |
| TCI Chemical | A0381 | 2-Amino-5-nitrothiazole >98.0%(HPLC)(T) | 121-66-4 | 500g | $993 | 2023-06-20 | Buy |
2-Amino-5-nitrothiazole Chemical Properties,Uses,Production
Uses
Niltazoxanide USP Related Compound A 2-Amino-5-nitrothiazole.
Chemical Properties
greenish yellow, to orange or brown powder
Uses
2-Amino-5-nitrothiazole was used as diazo component in the synthesis of monoazo disperse dyes. It was used as matrix during matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of oligonucleotide and protein.
Definition
ChEBI: 2-Amino-5-nitrothiazole is a member of thiazoles and a C-nitro compound.
Production Methods
Early production of 2-Amino-5-nitrothiazole was based on nitration of 2-acetylaminothiazole and careful hydrolysis. Direct nitration of 2-aminothiazole gives a cleaner product and is best achieved by adding 2-aminothiazole nitrate [57530-25-3] to concentrated sulfuric acid at 0 – 10 ℃. This process and the nitration of o-anisidine are the only large-scale processes based on rearrangement of an amine nitrate, and both are potentially hazardous due to the possibility of runaway exothermic reactions.
General Description
Greenish-yellow to orange-yellow fluffy powder or a brown chunky powder. Slightly bitter taste. Used as a veterinary medicine.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2-Amino-5-nitrothiazole may be sensitive to light. Incompatible with nitric acid and sulfuric acid. Also incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides. A preparative hazard .
Fire Hazard
Flash point data for 2-Amino-5-nitrothiazole are not available. 2-Amino-5-nitrothiazole is probably combustible.
Safety Profile
Poison by intraperitoneal route. Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SO,. Incompatible with HNO3 and H2SO4. An antiprotozoal agent.
Potential Exposure
2-Amino-5-nitrothiazole is a synthetic veterinary antiprotozoal agent used since 1950 to treat farm fowl and pigeons. It is also used as an intermediate in manufacturing a group of dyes known as disperse azo dyes. It is not known to occur as a natural product. People may be exposed to 2-amino-5-nitrothiazole through contact with birds treated with the drug, releases from poultry farms, and occupational exposures in the dye industry.
2-Amino-5-nitrothiazole Preparation Products And Raw materials
Raw materials
Preparation Products
1of4
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 | sales@qinmuchem.com | China | 1008 | 58 |
| Hangzhou Verychem Science And Technology Co.Ltd | +86-86-57188162785 13606544505 | lucy@verychem.com | China | 1114 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 5944 | 58 |
| Anhui Royal Chemical Co., Ltd. | +86-025-86655873 +8613962173137 | marketing@royal-chem.com | China | 199 | 55 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Shandong Juchuang Chemical Co., LTD | +16837774622 | admin@juchuangchem.com | China | 295 | 58 |
Related articles
- Synthesis of 2-Amino-5-nitrothiazole
- A new synthetic process for 2-Amino-5-nitrothiazole avoids dangerous nitration and rearrangement procedures.
- May 8，2024
View Lastest Price from 2-Amino-5-nitrothiazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-08 | 2-Amino-5-nitrothiazole
121-66-4
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-08-08 | 2-Amino-5-nitrothiazole
121-66-4
|
US $85.00 / KG | 1KG | 99% | 20tons | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-08-08 | 2-Amino-5-nitrothiazole
121-66-4
|
US $0.00 / Kg/Bag | 1KG | 99% | 20ton | Hebei Mujin Biotechnology Co.,Ltd |
-
- 2-Amino-5-nitrothiazole
121-66-4
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2-Amino-5-nitrothiazole
121-66-4
- US $85.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 2-Amino-5-nitrothiazole
121-66-4
- US $0.00 / Kg/Bag
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
