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ChemicalBook >> CAS DataBase List >>BT317

BT317

CAS No.
38485-94-8
Chemical Name:
BT317
Synonyms
BT317;2H-1-Benzopyran-3-carboxamide, 6-chloro-N-(4-methoxyphenyl)-2-oxo-
CBNumber:
CB514213912
Molecular Formula:
C17H12ClNO4
Molecular Weight:
329.74
MDL Number:
MOL File:
38485-94-8.mol
Last updated:2025-05-19 13:47:35

BT317 Properties

Boiling point 596.062±50.00 °C(Press: 760.00 Torr)(predicted)
Density 1.436±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 11.228±0.70(predicted)
form Solid
color Off-white to yellow

BT317 Chemical Properties,Uses,Production

Uses

BT317 is a blood-brain transmissible mitochondrial Lon peptidase I (LonP1) and CT-L proteasome inhibitor. BT317 can increase the production of reactive oxygen species (ROS) and induce apoptosis in astrocytoma cells. BT317 has antitumor activity[1].

References

[1] Douglas C, et al. Dual targeting of mitochondrial Lon peptidase 1 and chymotrypsin-like protease by small molecule BT317, as potential therapeutics in malignant astrocytoma. bioRxiv, 2023: 2023.04. 13.536816.

BT317 Preparation Products And Raw materials

Raw materials

Preparation Products

BT317 Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4770 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 24977 58
BT317 2H-1-Benzopyran-3-carboxamide, 6-chloro-N-(4-methoxyphenyl)-2-oxo- 38485-94-8