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ChemicalBook >> CAS DataBase List >>Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl-

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl-

CAS No.
2457245-94-0
Chemical Name:
Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl-
Synonyms
PI3K/Akt/mTOR-IN-3;Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl-
CBNumber:
CB511783519
Molecular Formula:
C34H51NO2
Molecular Weight:
505.77
MDL Number:
MOL File:
2457245-94-0.mol
Last updated:2025-04-30 08:50:00

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- Properties

Boiling point 615.3±55.0 °C(Predicted)
Density 1.05±0.1 g/cm3(Predicted)
pka 15.89±0.70(Predicted)

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- Chemical Properties,Uses,Production

Uses

PI3K/Akt/mTOR-IN-3 (compound 3d) is a potent PI3K/AKT/mTOR inhibitor. PI3K/Akt/mTOR-IN-3 displays the inhibitory activity in MCF-7, HeLa and HepG2 cells, with IC50 values of 0.77, 1.23, and 4.57μM, respectively. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 and HeLa cells at the concentration of 4 μM. PI3K/Akt/mTOR-IN-3 induces cell apoptosis and S phase arrest[1].

References

[1] Wang SS, et al. Synthesis and antitumor activity of α,β-unsaturated carbonyl moiety- containing oleanolic acid derivatives targeting PI3K/AKT/mTOR signaling pathway. Bioorg Chem. 2020 Aug;101:104036. DOI:10.1016/j.bioorg.2020.104036

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- Preparation Products And Raw materials

Raw materials

Preparation Products

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19930 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 25122 58

View Lastest Price from Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PI3K/Akt/mTOR-IN-3 pictures 2025-04-30 PI3K/Akt/mTOR-IN-3
2457245-94-0
 US $1980.00-2500.00 / mg 10g TargetMol Chemicals Inc.
Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- PI3K/Akt/mTOR-IN-3 2457245-94-0