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ChemicalBook >> CAS DataBase List >>Ezetimibe Impurity

Ezetimibe Impurity

CAS No.
1510820-22-0
Chemical Name:
Ezetimibe Impurity
Synonyms
Ezetimibe-11;Ezetimibe IMP;Ezetimibe Impuriry L;Ezetimibe Impurity I;Ezetimibe Impurity 129;3-Dehydroxy Ezetimibe Open Ring Impurity;N,5-Bis(4-fluorophenyl)-2R-(4-hydroxybenzyl)pentanamide;(R)-N,5-bis(4-fluorophenyl)-2-(4- hydroxybenzyl)pentanamide;Ezetimibe impuriry 13/(R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide;(R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide? (Ezetimibe Impurity）
CBNumber:
CB42681351
Molecular Formula:
C24H23F2NO2
Molecular Weight:
395.45
MDL Number:
MOL File:
1510820-22-0.mol
Last updated:2023-04-23 13:52:06

Ezetimibe Impurity Properties

Boiling point 610.4±55.0 °C(Predicted)
Density 1.246±0.06 g/cm3(Predicted)
solubility Dichloromethane; DMSO; Ethyl Acetate
form Solid
pka 10.04±0.15(Predicted)
color White

Ezetimibe Impurity Chemical Properties,Uses,Production

Uses

3-Dehydroxy Ezetimibe Open Ring Impurity is an impurity in the synthesis of 3-Dehydroxy Ezetimibe, a derivative of Ezetimibe (E975000), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.

Ezetimibe Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Ezetimibe IMP (R)-N,5-bis(4-fluorophenyl)-2-(4- hydroxybenzyl)pentanamide (2R,3R,6S)-6-(4-fluorophenyl)-2-(4-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran-3-carboxylic acid N,5-Bis(4-fluorophenyl)-2R-(4-hydroxybenzyl)pentanamide Benzenepentanamide, 4-fluoro-N-(4-fluorophenyl)-α-[(4-hydroxyphenyl)methyl]-, (αR)- 3-Dehydroxy Ezetimibe Open Ring Impurity Ezetimibe-11 Ezetimibe impuriry 13/(R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide Ezetimibe Impurity I Ezetimibe Impuriry L Ezetimibe Impurity 129 (R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide? (Ezetimibe Impurity） 1510820-22-0 C24H23F2NO2