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ChemicalBook >> CAS DataBase List >>2,4-Pyrimidinediamine, N2-[3-fluoro-4-(1-piperazinyl)phenyl]-N4-(8-methyl-4-cinnolinyl)-

2,4-Pyrimidinediamine, N2-[3-fluoro-4-(1-piperazinyl)phenyl]-N4-(8-methyl-4-cinnolinyl)-

CAS No.
2785430-87-5
Chemical Name:
2,4-Pyrimidinediamine, N2-[3-fluoro-4-(1-piperazinyl)phenyl]-N4-(8-methyl-4-cinnolinyl)-
Synonyms
ALK5-IN-31;2,4-Pyrimidinediamine, N2-[3-fluoro-4-(1-piperazinyl)phenyl]-N4-(8-methyl-4-cinnolinyl)-
CBNumber:
CB412746677
Molecular Formula:
C23H23FN8
Molecular Weight:
430.48
MDL Number:
MOL File:
2785430-87-5.mol
Last updated:2025-04-17 18:22:24

2,4-Pyrimidinediamine, N2-[3-fluoro-4-(1-piperazinyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- Properties

Boiling point 685.8±65.0 °C(Predicted)
Density 1.356±0.06 g/cm3(Predicted)
pka 8.76±0.10(Predicted)

2,4-Pyrimidinediamine, N2-[3-fluoro-4-(1-piperazinyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- Chemical Properties,Uses,Production

Uses

ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1].

References

[1] Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1.

2,4-Pyrimidinediamine, N2-[3-fluoro-4-(1-piperazinyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

2,4-Pyrimidinediamine, N2-[3-fluoro-4-(1-piperazinyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19904 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 21356 58

View Lastest Price from 2,4-Pyrimidinediamine, N2-[3-fluoro-4-(1-piperazinyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ALK5-IN-31 pictures 2025-05-01 ALK5-IN-31
2785430-87-5
 US $1520.00-2500.00 / mg 10g TargetMol Chemicals Inc.
  • ALK5-IN-31 pictures
  • ALK5-IN-31
    2785430-87-5
  • US $1520.00-2500.00 / mg
  • TargetMol Chemicals Inc.
2,4-Pyrimidinediamine, N2-[3-fluoro-4-(1-piperazinyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- ALK5-IN-31 2785430-87-5