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ChemicalBook >> CAS DataBase List >>Mal-PEG5-PFP

Mal-PEG5-PFP

CAS No.
1807512-46-4
Chemical Name:
Mal-PEG5-PFP
Synonyms
Mal-PEG5-PFP;Mal-PEG5-OPFP;perfluorophenyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oate;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,3,4,5,6-pentafluorophenyl ester
CBNumber:
CB33062543
Molecular Formula:
C23H26F5NO9
Molecular Weight:
555.45
MDL Number:
MFCD26127797
MOL File:
1807512-46-4.mol
Last updated:2025-04-18 09:52:08

Mal-PEG5-PFP Properties

Boiling point 594.2±50.0 °C(Predicted)
Density 1.376±0.06 g/cm3(Predicted)
pka -2.34±0.20(Predicted)

Mal-PEG5-PFP price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-21840 Mal-PEG5-PFP 98% 1807512-46-4 100mg $450 2021-12-16 Buy
BroadPharm BP-21840 Mal-PEG5-PFP 98% 1807512-46-4 250mg $780 2021-12-16 Buy
Apolloscientific BIPG1512 Mal-PEG5-PFP 1807512-46-4 100mg $797 2021-12-16 Buy
BroadPharm BP-21840 Mal-PEG5-PFP 98% 1807512-46-4 500mg $1170 2021-12-16 Buy
Product number Packaging Price Buy
BP-21840 100mg $450 Buy
BP-21840 250mg $780 Buy
BIPG1512 100mg $797 Buy
BP-21840 500mg $1170 Buy

Mal-PEG5-PFP Chemical Properties,Uses,Production

Description

Mal-PEG5-PFP is a PEG linker containing maleimide and PFP moieties. Maleimides are thiol-reactive and react between pH 6.5 and 7.5 to form thiolester bonds. PFP moieties are amine-reactive and are less susceptible to undergo hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.

Uses

Mal-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG5-PFP Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 36)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 32367 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd
+8618235132063 sales@tihondan.com China 3767 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 1924344760@confluore.cn China 2997 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39927 58
Bide Pharmatech Ltd. 400-164-7117 13681763483 product02@bidepharm.com China 42446 60
Hunan HuaTeng Pharmaceutical Co., Ltd., 400-8592883 sales@huatengsci.com China 5874 58
Jinan elephant international trading co., LTD 13006575422@163.com China 6355 58

View Lastest Price from Mal-PEG5-PFP manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mal-PEG5-PFP ester pictures 2025-06-07 Mal-PEG5-PFP ester
1807512-46-4
US $0.00 / mg 250mg >98.00% 250mg Xian confluore Biological Technology Co., Ltd.
  • Mal-PEG5-PFP ester pictures
  • Mal-PEG5-PFP ester
    1807512-46-4
  • US $0.00 / mg
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.
Mal-PEG5-PFP 4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,3,4,5,6-pentafluorophenyl ester perfluorophenyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oate Mal-PEG5-OPFP 1807512-46-4 C23H26F5NO9 peg