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ChemicalBook >> CAS DataBase List >>PD 117519

PD 117519

CAS No.
96392-15-3
Chemical Name:
PD 117519
Synonyms
CI 947;PD 11751;PD 117519;PD 117519,R;PD 117519 (CI947);PD 117519, 10 mM in DMSO;N-[(R)-Indan-1-yl]adenosine;N-[(1R)-Indan-1-yl]adenosine;(R)-N-(2,3-Dihydro-1H-indenyl)adenosine;PD-117519;PD 117519;PD117519;CI 947;CI947
CBNumber:
CB31872452
Molecular Formula:
C19H21N5O4
Molecular Weight:
383.4
MDL Number:
MFCD00876438
MOL File:
96392-15-3.mol
MSDS File:
SDS
Last updated:2025-04-29 09:03:59

PD 117519 Properties

storage temp. 2-8°C
solubility DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2mg/mL; DMSO: 5mg/mL; Ethanol: 0.1mg/mL
form A solid
color White to off-white
InChIKey FSKMJUWPFLDDRS-BYMDKACISA-N
SMILES OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N[C@H]3C4=C(C=CC=C4)CC3)N=C2)[C@H](O)[C@@H]1O

PD 117519 price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 28444 PD 117519 96392-15-3 5mg $57 2024-03-01 Buy
Cayman Chemical 28444 PD 117519 96392-15-3 10mg $100 2024-03-01 Buy
Cayman Chemical 28444 PD 117519 96392-15-3 25mg $208 2024-03-01 Buy
Cayman Chemical 28444 PD 117519 96392-15-3 50mg $384 2024-03-01 Buy
TRC D449160 (R)-N-(2,3-Dihydro-1H-indenyl)adenosine 96392-15-3 50mg $340 2021-12-16 Buy
Product number Packaging Price Buy
28444 5mg $57 Buy
28444 10mg $100 Buy
28444 25mg $208 Buy
28444 50mg $384 Buy
D449160 50mg $340 Buy

PD 117519 Chemical Properties,Uses,Production

Uses

N6-Substituted adenosine receptor agonist; a potential antihypertensive agent.

in vitro

PD 117519 (2-10 mg/kg; oral administration; 16-24 hours; male beagle dogs) treatment produces significant hemodynamic changes at Tmax (4 hours) follows by acute coronary vascular injury that is evident at 16 hours postdosing.Treatment with 2 or 10 mg/kg of PD 117519 produces significant increases in mean heart rate and decreases in mean indirectsystolic blood pressure at time of highest drug exposure, 4 hours postdosing.

in vivo

PD 117519 (2-10 mg/kg; oral administration; 16-24 hours; male beagle dogs) treatment produces significant hemodynamic changes at Tmax (4 hours) follows by acute coronary vascular injury that is evident at 16 hours postdosing.Treatment with 2 or 10 mg/kg of PD 117519 produces significant increases in mean heart rate and decreases in mean indirectsystolic blood pressure at time of highest drug exposure, 4 hours postdosing[3].

Animal Model:24 male beagle dogs (8-12 months old)[3]
Dosage:2 mg/kg or 10 mg/kg
Administration:Oral administration; 16 hours and 24 hours
Result:Increased in mean heart rate and decreased in mean indirectsystolic blood pressure at time of highest drug exposure. Induced acute coronary arteriopathy. The endothelium also appears injured.

PD 117519 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 75)Suppliers
Supplier Tel Email Country ProdList Advantage
PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD
0371-55159968 18137130222 haifeng.zhang@pannacean.com China 715 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10406 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5745 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32376 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30230 58
NewCan Biotech Limited 		+86-0571-86912261 +8613735419629 sales@newcanbio.com China 9985 58
LEAP CHEM CO., LTD. 		+86-852-30606658 19957148339; market18@leapchem.com China 24727 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 38838 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58

View Lastest Price from PD 117519 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PD 117519 pictures 2025-04-29 PD 117519
96392-15-3
 US $50.00-148.00 / mg 99.98% 10g TargetMol Chemicals Inc.
  • PD 117519 pictures
  • PD 117519
    96392-15-3
  • US $50.00-148.00 / mg
  • 99.98%
  • TargetMol Chemicals Inc.

PD 117519 Spectrum

(R)-N-(2,3-Dihydro-1H-indenyl)adenosine N-[(1R)-Indan-1-yl]adenosine N-[[(R)-2,3-Dihydro-1H-inden]-1α-yl]adenosine CI 947 N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine PD 117519 N-[(R)-Indan-1-yl]adenosine Adenosine, N-[(1R)-2,3-dihydro-1H-inden-1-yl]- PD 117519,R PD 11751 PD-117519;PD 117519;PD117519;CI 947;CI947 N-[(R)-Indan-1-yl] adenosine, Drug, N-substituted adenosine receptor agonist, a potential antihypertensive agent N-[(R)-Indan-1-yl]adenosine, PD-117519, CI947 CI-947,PD-117519,Adenosine Receptor,Inhibitor,P1 receptor,PD117519,PD 117519,inhibit,CI 947 PD 117519 (CI947) (2R,3R,4S,5R)-2-(6-(((R)-2,3-Dihydro-1H-inden-1-yl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol PD 117519, 10 mM in DMSO 96392-15-3 Bases & Related Reagents Carbohydrates & Derivatives Intermediates & Fine Chemicals Nucleotides Pharmaceuticals