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ChemicalBook >> CAS DataBase List >>(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol

(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol

CAS No.
142217-78-5
Chemical Name:
(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol
Synonyms
Entecavir-5;Entecavir E5;N-oxide impurity1;Entecavir Impurity 1;Entecavir Impurity 53;Entecavir Impurity 13;Entecavir InterMediate V;Entecavir intermediate N5;ENTECAVIR INTERMEDIATE (5TH);Entecavir InterMediate (CAS # 142217-78-5)
CBNumber:
CB31450658
Molecular Formula:
C52H49N5O5
Molecular Weight:
823.98
MDL Number:
MFCD09750978
MOL File:
142217-78-5.mol
MSDS File:
SDS
Last updated:2025-07-04 15:16:11

(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol Properties

Melting point >87°C (dec.)
Density 1.23
storage temp. 2-8°C
solubility Acetonitrile (Slightly, Sonicated), DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
pka 13.87±0.70(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic
InChIKey ZLWZEFPIJWNPCO-ABKHIKNWSA-N
SMILES [C@@H]1(O)[C@@H](N2C3C(N=C2)=C(OCC2=CC=CC=C2)N=C(NC(C2=CC=C(OC)C=C2)(C2=CC=CC=C2)C2=CC=CC=C2)N=3)C[C@H](OCC2=CC=CC=C2)[C@H]1COCC1=CC=CC=C1
CAS DataBase Reference 142217-78-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 090535 (1S,2S,3S,5S)-3-(Benzyloxy)-5-(6-(benzyloxy)-2-(((4-methoxyphenyl)diphenylmethylamino)-9H-purin-9-yl)-2-((benzyloxy)methyl)cyclopentanol 95+% 142217-78-5 250mg $492 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000820 CYCLOPENTANOL, 5-[2-[[(4-METHOXYPHENYL)DIPHENYLMETHYL]AMINO]-6-(PHENYLMETHOXY)-9H-PURIN-9-YL]-3-(PHENYLMETHOXY)-2-[(PHENYLMETHOXY)METHYL]-, [1S-(1ALPHA,2BETA,3ALPHA,5BETA)] 95.00% 142217-78-5 5MG $503.99 2021-12-16 Buy
AK Scientific W3097 (1S,2S,3S,5S)-3-(benzyloxy)-5-(6-(benzyloxy)-2-(((4-methoxyphenyl)diphenylmethyl)amino)-9H-purin-9-yl)-2-((benzyloxy)methyl)cyclopentanol 142217-78-5 250mg $714 2021-12-16 Buy
Matrix Scientific 090535 (1S,2S,3S,5S)-3-(Benzyloxy)-5-(6-(benzyloxy)-2-(((4-methoxyphenyl)diphenylmethylamino)-9H-purin-9-yl)-2-((benzyloxy)methyl)cyclopentanol 95+% 142217-78-5 1g $1092 2021-12-16 Buy
AK Scientific W3097 (1S,2S,3S,5S)-3-(benzyloxy)-5-(6-(benzyloxy)-2-(((4-methoxyphenyl)diphenylmethyl)amino)-9H-purin-9-yl)-2-((benzyloxy)methyl)cyclopentanol 142217-78-5 1g $1524 2021-12-16 Buy
Product number Packaging Price Buy
090535 250mg $492 Buy
NUC0000820 5MG $503.99 Buy
W3097 250mg $714 Buy
090535 1g $1092 Buy
W3097 1g $1524 Buy

(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol Chemical Properties,Uses,Production

Uses

Entecavir-?5 is used in the preparation of the anti-?HBV drug Entecavir.

(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol Preparation Products And Raw materials

Global( 191)Suppliers
Supplier Tel Email Country ProdList Advantage
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8615965530500 nickzhang@hangyubiotech.com China 10987 58
Nanjing Gold Pharmaceutical Technology Co. Ltd. 		025-84209270 15906146951 CHINA 115 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21622 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Lianyungang happen teng technology co., LTD 		15950718863 wang666xt@163.com CHINA 295 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29855 58
TianYuan Pharmaceutical CO.,LTD 		+86-755-23284190 13684996853 sales@tianpharm.com CHINA 304 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Jinan Finer Chemical Co., Ltd 		+86-531-88989536 +86-15508631887 sales@finerchem.com China 2955 58

View Lastest Price from (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol pictures 2025-06-03 (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol
142217-78-5
 US $150.00-880.00 / g 5g 99% 50 Zibo Hangyu Biotechnology Development Co., Ltd
(1S,2S,3S,5S)-5-(2-((4-methoxyphenyl)diphenylmethylamino)-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-((benzyloxy)methyl)cyclopentanol pictures 2024-03-28 (1S,2S,3S,5S)-5-(2-((4-methoxyphenyl)diphenylmethylamino)-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-((benzyloxy)methyl)cyclopentanol
142217-78-5
 US $0.00 / kg 25kg HPLC>98%;ee%>98.5 Inquiry PNP Biotech Co. Ltd
(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol pictures 2020-04-25 (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol
142217-78-5
 US $0.10 / KG 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd
(2R,3S,5S)-3-(Benzyloxy)-5-(6-benzyloxy)-2-(4-methyoxyphenyl)diphenylmethylamino)-9H-purin-9-yl)-2-benzyloxymethyl)cyclopentanol (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9- (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol ,99% [1S-(1α,2β,3α,5β)]-5-[2-[[(4-Methoxyphenyl)-diphenylMethyl]aMino]-6-(phenylMethoxy)-9H- purin-9-yl]-3-(phenylMethoxy)-2-[(phenyl-Methoxy)Methyl]cyclopentanol Entecavir InterMediate V (1S,2S,3S,5S)-5-(2-((4-Methoxyphenyl)diphenylMethylaMino)-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-((benzyloxy)Methyl)cyclopentanol Entecavir-5 (1S,2S,3S,5S)-3-(benzyloxy)-5-(6-(benzyloxy)-2-(((4-Methoxyphenyl)diphenylMethyl)aMino)-9H-purin-9-yl)-2-((benzyloxy)Methyl)cyclopentanol (1S,3R,4S)-3-(benzyloxy-5-[6-(benzyloxy)-2 -((4-Methoxyphenyl)diphenylMethylaMino) -9H- purin-9-yl]-2-(benzyloxyMethyl)cyclopentanol Entecavir InterMediate (CAS # 142217-78-5) (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-Methoxyphenyl)diphenylMethyl]aMino]-6-(phenylMethoxy)-9H-purin-9-yl]-2-(benzyloxyMethyl)cyclopentanol (interMediate step 4) (1S,2S,3S,5S)-3-BENZYLOXY)-5(6-BENZYLOXY)-2-((4-METHOXYPHENYL)DIPHENYLMETHYLAMINO)-9H-PURIN-9-YL)-2-(BENZYLOXYMETH (2R,3S,5S)-3-(Benzyloxy)-5-[6-(benzyloxy)-2-{[(4-Methoxyphenyl)(diphenyl)Methyl]aMino}-9H-purin-9-yl]-2-[(benzyloxy)Methyl]cyclopentanol (2R,3S,5S)-3-(benzyloxy)-5-[6-(benzyloxy)-2-{[(4-Methoxyphenyl)diphenylMethyl]aMino}-9H-purin-9-yl]-2-[(benzyloxy)Methyl]cyclopentan-1-ol (1S,2S,3S,5S)-3-(Benzyloxy)-5-(6-(benzyloxy)-2-(((4-methoxyphenyl)diphenylmethyl amino)-9H-purin- (1S,2S,3S,5S)-5-[2-[[(4-Methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]cyclopentanol Entecavir E5 (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol###142217-78-5 (1S,2S,3S,5S)-3-(Benzyloxy)-5-(6-(benzyloxy)-2-(((4-methoxyphenyl)diphenylmethylamino)-9H-puri (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-pu ENTECAVIR INTERMEDIATE (5TH) 2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-a(benzyloxymethyl)cyclopentanol Entecavir Impurity 53 (1S,2S,3S,5S)-3-(benzyloxy)-5-[6-(benzyloxy)-2-{[(4-methoxyphenyl)diphenylmethyl]amino}-9H-purin-9-yl]-2-[(benzyloxy)methyl]cyclopentan-1-ol 5-[2-[[(4-methoxyphenyl)-diphenylmethyl]amino]-6-phenylmethoxy-9-purinyl]-3-phenylmethoxy-2-(phenylmethoxymethyl)-1-cyclopentanol The China supplier of Entecavir Intermediate Cas:142217-78-5 Entecavir intermediate N5 Entecavir Impurity 13 Entecavir Impurity 1 N-oxide impurity1 Cyclopentanol, 5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (1S,2S,3S,5S)- 5-[2-[[(4-Methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]cyclopentanol (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmet... "(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)" (1S,2S,3S,5S)-5-[2-[[(4-Methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phen (2R,3S,5S)-3- (Benzyloxy)-5-[2-[[(4-methoxyphenyl)- diphenylmethyl]amino]-6- (phenylmethoxy)-9H-purin-9-yl]- 2- (benzyloxymethyl) cyclopentanol (Ent-V) (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylm (1S,2S,3S,5S)-3-(Benzyloxy)-5-(6-(benzyloxy)-2-(((4-methoxyphenyl)diphenylmethyl)amino)-9H-purin-9-yl)-2-((benzyloxy)methyl)cyclopentan-1-ol - [B88612] 142217-78-5 42217-78-5 C52H49N5O5