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ChemicalBook >> CAS DataBase List >>1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)-

1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)-

CAS No.
2416873-72-6
Chemical Name:
1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)-
Synonyms
KI-ARv-03;1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)-
CBNumber:
CB312153931
Molecular Formula:
C14H21N5
Molecular Weight:
259.35
MDL Number:
MOL File:
2416873-72-6.mol
Last updated:2025-01-27 09:38:02

1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)- Properties

Density 1.34±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 10.40±0.40(Predicted)
form (Powder or Lyophilized powder or film or oil)
color colorless to brown-yellow
UNSPSC Code 12352200
NACRES NA.77

1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)- Chemical Properties,Uses,Production

Biological Activity

KI-ARv-03 is a cell penetrant, potent and selective inhibitor of CDK9 th at th at reduces AR-driven transcription and proliferation in prostate cancer cells. KI-ARv-03 modulates AR and AR-V7-dependent transcription in 22Rv1 cells. It exhibits potent anti-tumor activity in castration-resistant prostate cancer (CRPC) models.

1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)- Preparation Products And Raw materials

Raw materials

Preparation Products

1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)- Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Merck KGaA 21-20338288 ordercn@merckgroup.com China 6394 58
Supplier Advantage
Merck KGaA 58
1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)- KI-ARv-03 2416873-72-6