午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

ChemicalBook >> CAS DataBase List >>BI-409306

BI-409306

CAS No.
1189767-28-9
Chemical Name:
BI-409306
Synonyms
CS-2883;BI-409306;Osoresnontrine;BI 409306 (BI-409306;BI-409306 (Osoresnontrine);BI 409306;BI-409306;BI409306;Osoresnontrine, 10 mM in DMSO;Osoresnontrine,Inhibitor,BI409306,Phosphodiesterase (PDE),inhibit,BI 409306;6-(pyridin-2-ylmethyl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one;6-(Pyridin-2-ylmethyl)-1-(tetrahydro-2H-pyran-4-yl)-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
CBNumber:
CB24668895
Molecular Formula:
C16H17N5O2
Molecular Weight:
311.34
MDL Number:
MFCD31746892
MOL File:
1189767-28-9.mol
Last updated:2025-04-17 18:22:24

BI-409306 Properties

Boiling point 559.8±60.0 °C(Predicted)
Density 1.48±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:62.0(Max Conc. mg/mL);199.14(Max Conc. mM)
form A crystalline solid
pka 3.94±0.12(Predicted)
color White to off-white
FDA UNII O9OC34WOAY

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

BI-409306 price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30375 BI-409306 1189767-28-9 1mg $62 2024-03-01 Buy
Cayman Chemical 30375 BI-409306 1189767-28-9 25mg $745 2024-03-01 Buy
Cayman Chemical 30375 BI-409306 1189767-28-9 5mg $194 2024-03-01 Buy
Cayman Chemical 30375 BI-409306 1189767-28-9 10mg $330 2024-03-01 Buy
ChemScene CS-0066455 BI-409306 99.97% 1189767-28-9 5mg $350 2021-12-16 Buy
Product number Packaging Price Buy
30375 1mg $62 Buy
30375 25mg $745 Buy
30375 5mg $194 Buy
30375 10mg $330 Buy
CS-0066455 5mg $350 Buy

BI-409306 Chemical Properties,Uses,Production

Uses

Osoresnontrine (BI-409306) is a potent and selective PDE9A inhibitor, with an IC50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A (IC50, 1.4 μM), PDE1C (IC50, 1.0 μM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 all > 10 μM); Osoresnontrine can be used in the research of memory enhancement in CNS disorders.

IC 50

PDE9A: 52 nM (IC50); PDE1C: 1 μM (IC50); PDE1A: 1.4 μM (IC50)

References

[1] Cornelia Dorner-Ciossek, et al. BI 409306, a novel phosphodiesterase 9A inhibitor, part I: potency, selectivity and in-vitro functional characterization on synaptic plasticity. International Congress on Schizophrenia Research.

BI-409306 Preparation Products And Raw materials

Raw materials

Preparation Products

BI-409306 Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32286 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38669 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 12952 65
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4621 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58

View Lastest Price from BI-409306 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Osoresnontrine pictures 2025-05-01 Osoresnontrine
1189767-28-9
 US $74.00-198.00 / mg 99.93% 10g TargetMol Chemicals Inc.
  • Osoresnontrine pictures
  • Osoresnontrine
    1189767-28-9
  • US $74.00-198.00 / mg
  • 99.93%
  • TargetMol Chemicals Inc.
BI-409306 BI 409306 (BI-409306 CS-2883 BI 409306;BI-409306;BI409306 6-(pyridin-2-ylmethyl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-6-(2-pyridinylmethyl)-1-(tetrahydro-2H-pyran-4-yl)- 6-(Pyridin-2-ylmethyl)-1-(tetrahydro-2H-pyran-4-yl)-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one Osoresnontrine Osoresnontrine,Inhibitor,BI409306,Phosphodiesterase (PDE),inhibit,BI 409306 BI-409306 (Osoresnontrine) Osoresnontrine, 10 mM in DMSO 1189767-28-9 118967-28-9