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ChemicalBook >> CAS DataBase List >>Ginsenoside Rd

Ginsenoside Rd

CAS No.
52705-93-8
Chemical Name:
Ginsenoside Rd
Synonyms
Chikusetsusaponin FK7;Gypenoside VIII;ginsenosideR;Panaxoside Rd;GINSENOSIDE RD;GINSENOOSIDERD;Sanchinoside Rd;Rd Ginsenoside Rd;Ginsenoside Rd-RM;Ginsenoside Rd(AS)
CBNumber:
CB1281187
Molecular Formula:
C48H82O18
Molecular Weight:
947.15
MDL Number:
MFCD00799993
MOL File:
52705-93-8.mol
Last updated:2025-07-17 08:36:09

Ginsenoside Rd Properties

Melting point 204～206℃
Boiling point 1015.6±65.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 12.85±0.70(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic
InChIKey FBFMBWCLBGQEBU-FIKSETHBNA-N
LogP 3.110 (est)
CAS DataBase Reference 52705-93-8(CAS DataBase Reference)
FDA UNII WB232T95AV
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  2-45
WGK Germany  3
HS Code  29389090
NFPA 704
0
2 0

Ginsenoside Rd price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89211 Ginsenoside Rd phyproof? Reference Substance 52705-93-8 10MG $316 2024-03-01 Buy
Sigma-Aldrich 01518 Ginsenoside Rd analytical standard 52705-93-8 10mg $396 2024-03-01 Buy
TCI Chemical G0550 Ginsenoside Rd 52705-93-8 25MG $173 2024-03-01 Buy
TCI Chemical G0550 Ginsenoside Rd 52705-93-8 100MG $432 2024-03-01 Buy
Cayman Chemical 15329 Ginsenoside Rd ≥98% 52705-93-8 1mg $32 2024-03-01 Buy
Product number Packaging Price Buy
PHL89211 10MG $316 Buy
01518 10mg $396 Buy
G0550 25MG $173 Buy
G0550 100MG $432 Buy
15329 1mg $32 Buy

Ginsenoside Rd Chemical Properties,Uses,Production

Description

Ginsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rd is a protopanaxadiol which is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions. Notably, ginsenoside Rd is converted to other ginsenosides in response to steaming or heating plant materials, leading to loss of these activities.

Chemical Properties

White to off-white crystals powder

Uses

Ginsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia.

Definition

ChEBI: Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. It has a role as a vulnerary, a neuroprotective agent, an apoptosis inducer, an anti-inflammatory drug, an immunosuppressive agent and a plant metabolite. It is a ginsenoside, a beta-D-glucoside and a tetracyclic triterpenoid. It is functionally related to a (20S)-ginsenoside Rg3.

in vivo

Ginsenosides Rd is a major compound isolated from Gynostemma pentaphyllum that holistically improves gut microenvironment and induces anti-polyposis in ApcMin/+ mice. Six-weeks-old mice are subjected to Ginsenoside Rd treatment, before the appearance of the intestinal polyps. All the mice are monitored for food intake, water consumption, and weight changes. Throughout the experiment, no Rb3/ Ginsenoside Rd-associated weight loss in mice is observed. In addition, none of the treated mice show variations in food and water consumption. Whereas, the number and size of the polyps are effectively reduced by Ginsenoside Rd treatments[3].

IC 50

NF-κB: 12.05 μM (IC50, in HepG2 cells); COX-2; L-type calcium channel; CYP2D6: 58 μM (IC50); CYP1A2: 78.4 μM (IC50); CYP3A4: 81.7 μM (IC50); CYP2C9: 85.1 μM (IC50)

Ginsenoside Rd Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 376)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618791163155 18791163155@163.com China 3457 58
Shaanxi Xianhe Biotech Co., Ltd 		+8617709210191 Jerry@xhobio.com China 885 58
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29731 60
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29855 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Shaanxi Pioneer Biotech Co., Ltd . 		+8613259417953 sales@pioneerbiotech.com China 1287 58
NanJing Spring & Autumn Biological Engineering CO., LTD. 		+8613815430202 sale02@cqherb.com CHINA 376 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58

View Lastest Price from Ginsenoside Rd manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ginsenoside Rd pictures 2025-07-17 Ginsenoside Rd
52705-93-8
 US $33.00-112.00 / mg 99.92% 10g TargetMol Chemicals Inc.
GINSENOSIDE Rd pictures 2025-07-16 GINSENOSIDE Rd
52705-93-8
 US $0.00 / kg 1kg 0.99 1000kg Shaanxi Xianhe Biotech Co., Ltd
Ginsenoside Rd pictures 2023-02-24 Ginsenoside Rd
52705-93-8
 US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • Ginsenoside Rd pictures
  • Ginsenoside Rd
    52705-93-8
  • US $33.00-112.00 / mg
  • 99.92%
  • TargetMol Chemicals Inc.
  • GINSENOSIDE Rd pictures
  • GINSENOSIDE Rd
    52705-93-8
  • US $0.00 / kg
  • 0.99
  • Shaanxi Xianhe Biotech Co., Ltd
  • Ginsenoside Rd pictures
  • Ginsenoside Rd
    52705-93-8
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
2-o-beta-d-glucopyranosyl-(3beta,12beta)-20-(beta-d-glucopyranosyloxy)-12-hydroxydammara-24-en-3-yl-beta-d-glucopyranoside GINSENOSIDE RD beta-d-glucopyranoside,(3-beta,12-beta)-20-(beta-d-glucopyranosyloxy)-12-hydro (3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside xydammar-24-en-3-yl2-o-beta-d-glucopyranosyl- GINSENOOSIDERD Ginsenoside Rd (CAS# 52705-93-87) GINSENOSIDE Rd hplc Ginsenoside Rd std. GINSENOSIDE RD WITH HPLC (20S)-3β-[[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]oxy]-20-(β-D-glucopyranosyloxy)dammaran-24-ene-12β-ol (20S)-3β-[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-20-(β-D-glucopyranosyloxy)dammar-24-ene-12β-ol [20-(β-D-Glucopyranosyloxy)-12β-hydroxydammar-24-en-3β-yl]2-O-β-D-glucopyranosyl-β-D-glucopyranoside 20-(β-D-Glucopyranosyloxy)-12β-hydroxy-5α-dammar-24-ene-3β-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside 3β-[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-20-(β-D-glucopyranosyloxy)dammar-24-ene-12β-ol ginsenoside--Rd standard Ginsenoside Rd ,98% Herba Gynostemmatis Pentaphylli glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl2-O-β-D-glucopyranosyl- β-D-Glucopyranoside,(3β,12β)-20-(β-D- Ginsenoside Rd 52705-93-8 b-D-Glucopyranoside, (3b,12b)-20-(b-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-b-D-glucopyranosyl- Panaxoside Rd Sanchinoside Rd β-D-Glucopyranoside, (3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl- ginsenosideR 2-O-beta-Glucopyranosyl-(3beta,12beta)-20-beta-D-glucopyranosyloxy-12-hydroxydammar-24-en-3-yl-beta-D-glucopyranoside (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chikusetsusaponin FK7 Gypenoside VIII (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol Rd Ginsenoside Rd Ginsenoside Rd(AS) Ginsenoside Rd-RM β-?D-?Glucopyranoside, (3β,?12β)?-?20-?(β-?D-?glucopyranosyloxy)?-?12-?hydroxydammar-?24-?en-?3-?yl 2-?O-?β-?D-?glucopyranosyl- 52705-93-8 C48H82O19 Inhibitors reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Ginsenoside series chemical reagent pharmaceutical intermediate phytochemical The group of Ginsenosides Saponins