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ChemicalBook >> CAS DataBase List >>[3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine

[3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine

CAS No.
56173-05-8
Chemical Name:
[3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine
Synonyms
PCAF-IN-2;6-Hydrazineyl-3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazine;[3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine
CBNumber:
CB03911798
Molecular Formula:
C10H7F3N6
Molecular Weight:
268.1979896
MDL Number:
MOL File:
56173-05-8.mol
Last updated:2025-04-29 09:03:59

[3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine Properties

form Solid
color White to off-white

[3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine Chemical Properties,Uses,Production

Uses

PCAF-IN-2 (compound 17) is a potent PCAF inhibitor with an IC50 value of 5.31 μM. PCAF-IN-2 shows anti-tumour activity. CAF-IN-2 induces apoptosis and arrest the cell cycle at the G2/M phase[1].

IC 50

PCAF: 5.31 μM (IC50)

References

[1] Turky A, et al. Design, synthesis, and antitumor activity of novel compounds based on 1,2,4-triazolophthalazine scaffold: Apoptosis-inductive and PCAF-inhibitory effects. Bioorg Chem. 2020 Aug;101:104019. DOI:10.1016/j.bioorg.2020.104019

[3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine Preparation Products And Raw materials

Raw materials

Preparation Products

[3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19903 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 6453 55
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62321 58
Hubei wei shi reagent group ltd., company 027-59101766 13125137661 2853877621@qq.com China 7968 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 20701 58

View Lastest Price from [3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PCAF-IN-2 pictures 2025-04-29 PCAF-IN-2
56173-05-8
 US $996.00-766.00 / mg 10g TargetMol Chemicals Inc.
  • PCAF-IN-2 pictures
  • PCAF-IN-2
    56173-05-8
  • US $996.00-766.00 / mg
  • TargetMol Chemicals Inc.
[3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine PCAF-IN-2 6-Hydrazineyl-3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazine 56173-05-8