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ChemicalBook >> CAS DataBase List >>Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl-

Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl-

CAS No.
251994-14-6
Chemical Name:
Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl-
Synonyms
CAM-IN-1;ICAM-1 inhibitor 1;ICAM-1-IN-1, 10 mM in DMSO;ICAM 1 IN 1,inhibit,ICAM1IN1,Inhibitor,Integrin;4-(4-Bromophenoxy)-N-methylthieno[2,3-c]pyridine-2-carboxamide;Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl-
CBNumber:
CB03339721
Molecular Formula:
C15H11BrN2O2S
Molecular Weight:
363.23
MDL Number:
MOL File:
251994-14-6.mol
Last updated:2025-05-08 20:29:18

Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl- Properties

Melting point 78-80 °C
Boiling point 579.6±45.0 °C(Predicted)
Density 1.556±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 135 mg/mL (371.67 mM)
form Solid
pka 13.70±0.46(Predicted)
color White to off-white

Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-7225 ICAM-1-IN-1 99.96% 251994-14-6 5mg $500 2021-12-16 Buy
ChemScene CS-7225 ICAM-1-IN-1 99.96% 251994-14-6 10mg $850 2021-12-16 Buy
ChemScene CS-7225 ICAM-1-IN-1 99.96% 251994-14-6 25mg $1800 2021-12-16 Buy
ChemScene CS-7225 ICAM-1-IN-1 99.96% 251994-14-6 50mg $3000 2021-12-16 Buy
ChemScene CS-7225 ICAM-1-IN-1 99.96% 251994-14-6 100mg $4600 2021-12-16 Buy
Product number Packaging Price Buy
CS-7225 5mg $500 Buy
CS-7225 10mg $850 Buy
CS-7225 25mg $1800 Buy
CS-7225 50mg $3000 Buy
CS-7225 100mg $4600 Buy

Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl- Chemical Properties,Uses,Production

Uses

ICAM-1-IN-1 is a potent and selective inhibitor of E-selectin and ICAM-1 with IC50 values of 7 and 5 nM, respectively.

in vivo

ICAM-1-IN-1 shows significant efficacy in a rat rheumatoid arthritis model and in a mouse asthma model. ICAM-1-IN-1 reduces the width of inflamed ankles after the ninth day following treatment, but shows no efficacy in the acute phase. Treatment with ICAM-1-IN-1 (25 mg/kg) for 21 days significantly reduces the ankle inflammation of the arthritis rats. Significant reduction of eosinophils and serum-soluble ICAM-1 (sICAM-1) is observed[1].

References

[1] Zhu GD, et al. Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Arylmodifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides. J Med Chem. 2001 Oct 11;44(21):3469-87. DOI:10.1021/jm0101702

Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl- Suppliers

Global( 25)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32342 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38730 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7786 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
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BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58

View Lastest Price from Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ICAM-1-IN-1 pictures 2025-05-08 ICAM-1-IN-1
251994-14-6
 US $195.00-618.00 / mg 99.34% 10g TargetMol Chemicals Inc.
ICAM-1-IN-1 pictures 2025-05-08 ICAM-1-IN-1
251994-14-6
 US $195.00-618.00 / mg 99.34% 10g TargetMol Chemicals Inc.
  • ICAM-1-IN-1 pictures
  • ICAM-1-IN-1
    251994-14-6
  • US $195.00-618.00 / mg
  • 99.34%
  • TargetMol Chemicals Inc.
  • ICAM-1-IN-1 pictures
  • ICAM-1-IN-1
    251994-14-6
  • US $195.00-618.00 / mg
  • 99.34%
  • TargetMol Chemicals Inc.
Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl- CAM-IN-1 ICAM-1 inhibitor 1 ICAM 1 IN 1,inhibit,ICAM1IN1,Inhibitor,Integrin 4-(4-Bromophenoxy)-N-methylthieno[2,3-c]pyridine-2-carboxamide ICAM-1-IN-1, 10 mM in DMSO 251994-14-6