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ChemicalBook >> CAS DataBase List >>7,8-DIHYDRO-L-BIOPTERIN

7,8-DIHYDRO-L-BIOPTERIN

CAS No.
6779-87-9
Chemical Name:
7,8-DIHYDRO-L-BIOPTERIN
Synonyms
BH2;DIHYDROBIOPTERIN;7,8-dihydrobiopterin;Biopterin Impurity 1;Biopterin impurity 6;7,8-DIHYDRO-L-BIOPTERIN;Sapropterin Impurity 18;L-erythro-Dihydrobiopterin;L-erythro-7,8-Dihydrobiopterin;7,8-Dihydro-L-biopterin
CBNumber:
CB0320957
Molecular Formula:
C9H13N5O3
Molecular Weight:
239.23
MDL Number:
MFCD07375453
MOL File:
6779-87-9.mol
MSDS File:
SDS
Last updated:2025-07-04 15:01:33

7,8-DIHYDRO-L-BIOPTERIN Properties

Melting point >300°C dec.
Boiling point 470.8±55.0 °C(Predicted)
Density 1.88
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility Aqueous Acid (Slightly, Sonicated), Aqueous Base (Slightly), DMSO (Slightly)
form Solid
pka 10.47±0.20(Predicted)
color Pale Yellow to Brown
BRN 536551
Stability Hygroscopic
InChI InChI=1S/C9H13N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,6,15-16H,2H2,1H3,(H4,10,11,13,14,17)/t3-,6-/m0/s1
InChIKey FEMXZDUTFRTWPE-AWFVSMACSA-N
SMILES N1C2=C(N=C([C@@H](O)[C@@H](O)C)CN2)C(=O)NC=1N
CAS DataBase Reference 6779-87-9
UNSPSC Code 12352116
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
F  3-10

7,8-DIHYDRO-L-BIOPTERIN price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 37272 7,8-Dihydro-L-biopterin ≥94% (HPLC) 6779-87-9 10mg $121 2024-03-01 Buy
Sigma-Aldrich 37272 7,8-Dihydro-L-biopterin ≥94% (HPLC) 6779-87-9 50mg $470 2024-03-01 Buy
Cayman Chemical 81882 7,8-dihydro-L-Biopterin ≥97% 6779-87-9 5mg $45 2024-03-01 Buy
Cayman Chemical 81882 7,8-dihydro-L-Biopterin ≥97% 6779-87-9 10mg $72 2024-03-01 Buy
Cayman Chemical 81882 7,8-dihydro-L-Biopterin 6779-87-9 50mg $330 2024-03-01 Buy
Product number Packaging Price Buy
37272 10mg $121 Buy
37272 50mg $470 Buy
81882 5mg $45 Buy
81882 10mg $72 Buy
81882 50mg $330 Buy

7,8-DIHYDRO-L-BIOPTERIN Chemical Properties,Uses,Production

Description

BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.

Chemical Properties

Yellow Powder

Uses

BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.

Uses

An oxidation producct of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of G

Uses

The reduced form of Biopterin. An oxidation product of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.

Definition

ChEBI: L-erythro-7,8-dihydrobiopterin is a 7,8-dihydrobiopterin in which the 1,2-dihydroxypropyl group has (1R,2S)-configuration; naturally occurring form. It is an enantiomer of a D-erythro-7,8-dihydrobiopterin.

References

[1] shen r, alam a, zhang y. inhibition of gtp cyclohydrolase i by pterins[j]. biochimica et biophysica acta (bba)-general subjects, 1988, 965(1): 9-15.
[2] sugiyama t, levy b d, michel t. tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells[j]. journal of biological chemistry, 2009, 284(19): 12691-12700.

7,8-DIHYDRO-L-BIOPTERIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 7,8-DIHYDRO-L-BIOPTERIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7,8-Dihydro-L-biopterin pictures 2025-05-30 7,8-Dihydro-L-biopterin
6779-87-9
 US $60.00-230.00 / mg 100% 10g TargetMol Chemicals Inc.
7,8-dihydrobiopterin 7,8-DIHYDRO-L-BIOPTERIN 2-AMINO-6-(1R,2S-DIHYDROXYPROPYL)-7,8-DIHYDRO-4(1H)-PTERIDINONE BH2 DIHYDROBIOPTERIN 2-Amino-6-(1,2-dihydroxy-propyl)-7,8-dihydro-3H-pteridin-4-one 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone 2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydro-1H-pteridin-4-one 4(1H)-pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydro- L-erythro-7,8-Dihydrobiopterin L-erythro-Dihydrobiopterin 2-aMino-6-((1S,2R)-1,2-dihydroxypropyl)-7,8-dihydropteridin-4(3H)-one 1-(2-Amino-4-hydroxy-7,8-dihydropteridin-7-yl)propane-1,2-diol 4(3H)-Pteridinone, 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro- 2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-7,8-dihydropteridin-4(1H)-one Sapropterin Impurity 18 inhibit,7,8 Dihydro L biopterin,Inhibitor,7,8DihydroLbiopterin,Endogenous Metabolite Biopterin Impurity 1 Biopterin impurity 6 7,8-Dihydro-L-biopterin, 10 mM in DMSO 7,8-Dihydro-L-biopterin 6779-87-9 C9H13N5O3 Amines Bases & Related Reagents Chiral Reagents Heterocycles Intermediates & Fine Chemicals Nucleotides Pharmaceuticals All Inhibitors Inhibitors Neurochemicals