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ChemicalBook >> CAS DataBase List >>FR901465

FR901465

CAS No.
146478-73-1
Chemical Name:
FR901465
Synonyms
WB 2663C;FR901465;DQTXAXNYLWRTPB-NTVXLVODSA-N;(2S,3Z)-4-{[(2R,3R,5S,6S)-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]penta-2,4-dien-1-yl]oxan-3-yl]carbamoyl}but-3-en-2-yl acetate;2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-2,4-pentadien-1-yl]-2H-pyran-3-yl]-, (2Z,4S)-
CBNumber:
CB02716235
Molecular Formula:
C27H41NO9
Molecular Weight:
523.62
MDL Number:
MFCD28347814
MOL File:
146478-73-1.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:30

FR901465 Properties

Boiling point 735.6±60.0 °C(Predicted)
Density 1.25±0.1 g/cm3(Predicted)
pka 12.43±0.70(Predicted)

FR901465 Chemical Properties,Uses,Production

Uses

FR901465 is a potent anti-cancer and anti-tumor agent. FR901465 can be used for cancer research[1].

Definition

ChEBI: A spiro-epoxide with potent cytotoxic activity against human tumour cells. It is isolated from Pseudomonas sp. no.2663.

References

[1] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action. J Antibiot (Tokyo). 1996 Dec;49(12):1204-11. DOI:10.7164/antibiotics.49.1204
[2] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465. J Antibiot (Tokyo). 1997 Jan;50(1):96-9. DOI:10.7164/antibiotics.50.96
[3] Ratnakar N. Asolkar, et al. Discovery and Development of Natural Products for Pest Management. RETURN TO BOOKPREVCHAPTERNEXT

FR901465 Preparation Products And Raw materials

Raw materials

Preparation Products

FR901465 Suppliers

Global( 20)Suppliers
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BOC Sciences
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Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139 orders@jknbiochem.com China 5221 58
Nanjing Sunlida Biological Technology Co., Ltd. 025-57798810 sales@sunlidabio.com China 3239 55
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7786 56
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4645 55

146478-73-1(FR901465)Related Search:

FR901465 WB 2663C 2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-2,4-pentadien-1-yl]-2H-pyran-3-yl]-, (2Z,4S)- DQTXAXNYLWRTPB-NTVXLVODSA-N (2S,3Z)-4-{[(2R,3R,5S,6S)-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]penta-2,4-dien-1-yl]oxan-3-yl]carbamoyl}but-3-en-2-yl acetate 146478-73-1