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ChemicalBook >> CAS DataBase List >>LY 334370 HYDROCHLORIDE

LY 334370 HYDROCHLORIDE

CAS No.
182563-08-2
Chemical Name:
LY 334370 HYDROCHLORIDE
Synonyms
Y334370;LY 334370;Y 334370 HCL;LY 334370 HCL;LY 334370 hydrochlor;LY 334370 HYDROCHLORIDE;LY334370, 10 mM in DMSO;LY334370;LY-334370;LY 334370;LY-334370 hydrochloride hydrate;4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benazmide
CBNumber:
CB02459701
Molecular Formula:
C21H22FN3O
Molecular Weight:
351.42
MDL Number:
MFCD11519957
MOL File:
182563-08-2.mol
Last updated:2025-06-28 14:24:05

LY 334370 HYDROCHLORIDE Properties

Boiling point 479.1±45.0 °C(Predicted)
Density 1.267±0.06 g/cm3(Predicted)
storage temp. Store at +4°C
solubility H2O: ≥5mg/mL (warmed)
form powder
pka 13.98±0.43(Predicted)
color white to tan
FDA UNII 5Q7I1WL2UY

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338
WGK Germany  3

LY 334370 HYDROCHLORIDE price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0010 LY-334370 hydrochloride hydrate ≥98% (HPLC), powder 182563-08-2 5mg $130 2022-05-15 Buy
Sigma-Aldrich SML0010 LY-334370 hydrochloride hydrate ≥98% (HPLC), powder 182563-08-2 25mg $501 2022-05-15 Buy
Tocris 3079 LY334370hydrochloride ≥99%(HPLC) 182563-08-2 50 $713 2021-12-16 Buy
Tocris 3079 LY334370hydrochloride ≥99%(HPLC) 182563-08-2 10 $194 2021-12-16 Buy
ChemScene CS-0025021 LY334370 99.80% 182563-08-2 25mg $348 2021-12-16 Buy
Product number Packaging Price Buy
SML0010 5mg $130 Buy
SML0010 25mg $501 Buy
3079 50 $713 Buy
3079 10 $194 Buy
CS-0025021 25mg $348 Buy

LY 334370 HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

LY 334370 Hydrochloride is a 5-HT1f receptor agoniist used potentially in the treatment of migranes.

Biological Activity

Selective 5-HT 1F receptor agonist (K i values are 1.87, 16.4, > 100 (IC 50 ), 176, 189, 281, 1280, 1530, 1550, > 3000 (IC 50 ) and 3250 nM for 5-HT 1F , 5-HT 1A , 5-HT 4 , 5-HT 1E , 5-HT 1B , 5-HT 1D , 5-HT 2B , 5-HT 2A , 5-HT 7 , 5-HT 6 and 5-HT 2C receptors respectively). Displays antimigraine effects.

in vivo

Following intravenous administration of LY334370 at 3 mg/kg (n=3) or 10 mg/kg (n=6) electrical stimulation evokes an increase in dural blood vessel diameter of 135±6% and 106±11%, respectively, which is not significantly different from the respective control values. LY334370 has no effect on dural blood vessel diameter per se, since the actual dural blood vessel diameter is 43±4 arbitrary units before drug and 43±4 arbitrary units 15 min after injection of LY334370 (10 mg/kg)[1].

IC 50

5-HT1F Receptor: 1.6 nM (Ki)

LY 334370 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 60)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49733 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29804 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5745 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32376 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 38838 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69

View Lastest Price from LY 334370 HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LY334370 pictures 2025-06-28 LY334370
182563-08-2
 US $38.00-133.00 / mg 98.48% 10g TargetMol Chemicals Inc.
LY 334370 HYDROCHLORIDE pictures 2019-12-25 LY 334370 HYDROCHLORIDE
182563-08-2
 US $1.00 / g 1g 99.99% 200kg Career Henan Chemical Co
  • LY334370 pictures
  • LY334370
    182563-08-2
  • US $38.00-133.00 / mg
  • 98.48%
  • TargetMol Chemicals Inc.
LY 334370 HYDROCHLORIDE 4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamidehydrochloride 4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benazmide BenzaMide, 4-fluoro-N-[3-(1-Methyl-4-piperidinyl)-1H-indol-5-yl]- 4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide hydrochloride hydrate LY-334370 hydrochloride hydrate 4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benzamide hydrochloride 4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benazmide hydrochloride LY 334370 4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-indol-5-yl]-benzamide LY 334370 HCL LY334370;LY-334370;LY 334370 Y 334370 HCL Y334370 LY 334370 hydrochlor inhibit,Inhibitor,5-hydroxytryptamine Receptor,LY-334370,LY334370,Serotonin Receptor,5-HT Receptor LY334370, 10 mM in DMSO 182563-08-2 C21H22FN3OHCl