ChemicalBook >> CAS DataBase List >>NSC 366140
NSC 366140
- CAS No.
- 99009-20-8
- Chemical Name:
- NSC 366140
- Synonyms
- PD 115;Pd 115934;NSC 366140;Pd 115,934;Brn 4211902;Pyrazoloacridine;Pyrazoloacridine, 10 mM in DMSO;N,N-Dimethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-propanamine;Pyrazolo(3,4,5-kl)acridine-2(6H)-propanamine, N,N-dimethyl-9-methoxy-5-nitro-;Pyrazolo[3,4,5-kl]acridine-2(6H)-propanamine, 9-methoxy-N,N-dimethyl-5-nitro-
- CBNumber:
- CB01387979
- Molecular Formula:
- C19H21N5O3
- Molecular Weight:
- 367.4
- MDL Number:
- MFCD00667221
- MOL File:
- 99009-20-8.mol
Last updated:2025-07-17 15:37:33
| Boiling point | 584.3±50.0 °C(Predicted) |
|---|---|
| Density | 1.38±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| pka | 9.35±0.28(Predicted) |
| form | Solid |
| color | Light brown to orange |
| EWG's Food Scores | 1 |
| NCI Dictionary of Cancer Terms | pyrazoloacridine |
| FDA UNII | L24XJN68OW |
| NCI Drug Dictionary | pyrazoloacridine |
NSC 366140 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R169595 | (3-(9-METHOXY-5-NITRO-6H-PYRAZOLO(3,4,5-KL)ACRIDIN-2-YL)-PROPYL)-DIMETHYL-AMINE Aldrich | 99009-20-8 | 50mg | $179 | 2024-03-01 | Buy |
| ChemScene | CS-0033826 | Pyrazoloacridine ≥98.0% | 99009-20-8 | 5mg | $250 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0005673 | PYRAZOLOACRIDINE 95.00% | 99009-20-8 | 5MG | $501.64 | 2021-12-16 | Buy |
NSC 366140 Chemical Properties,Uses,Production
Uses
Pyrazoloacridine (NSC 366140), an intercalating agent with anti-cancer activity, inhibits the activity of topoisomerases 1 and 2. Pyrazoloacridine (NSC 366140) exhibits an IC50 of 1.25 μM in K562 myeloid leukemia cells for 24 h treatment[1][2].
References
[1] J S Sebolt, et al. Pyrazoloacridines, a new class of anticancer agents with selectivity against solid tumors in vitro. Cancer Res. 1987 Aug 15;47(16):4299-304. PMID:2440564
[2] A A Adjei, et al. Effect of pyrazoloacridine (NSC 366140) on DNA topoisomerases I and II. Clin Cancer Res. 1998 Mar;4(3):683-91. PMID:9533538
NSC 366140 Preparation Products And Raw materials
Raw materials
Preparation Products
NSC 366140 Suppliers
Global( 19)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32350 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2123 | 70 |
| Lanzhou Angeli Biochemical Technology Co., Ltd. | 0931-8235634 13321316780 | 1455540579@qq.com | China | 958 | 55 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29770 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24979 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9835 | 58 |
| Shandong Mingde Biotechnology Co., Ltd | 15553348166 | m15553348166@163.com | China | 9766 | 58 |
View Lastest Price from NSC 366140 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-17 | Pyrazoloacridine
99009-20-8
|
US $34.00-123.00 / mg | 99.72% | 10g | TargetMol Chemicals Inc. |
-
- Pyrazoloacridine
99009-20-8
- US $34.00-123.00 / mg
- 99.72%
- TargetMol Chemicals Inc.
Pyrazolo(3,4,5-kl)acridine-2(6H)-propanamine, N,N-dimethyl-9-methoxy-5-nitro-
(3-(9-METHOXY-5-NITRO-6H-PYRAZOLO(3,4,5-KL)ACRIDIN-2-YL)-PROPYL)-DIMETHYL-AMINE
NSC 366140
2,6-Dihydro-2-(3-dimethylaminopropyl)-9-methoxy-5-nitropyrazolo[3,4,5-kl]acridine
9-Methoxy-N,N-dimethyl-5-nitropyrazolo[3,4,5-kl]acridine-2(6H)-propane-1-amine
Pyrazoloacridine
1,2,6,10b-Tetrahydro-5-nitro-9-methoxy-2-[3-(dimethylamino)propyl]pyrazolo[3,4,5-kl]acridine
Brn 4211902
N,N-Dimethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-propanamine
Pd 115,934
Pd 115934
PD 115
tumor,Inhibitor,leukemia,inhibit,solid,Apoptosis,NSC366140,carcinoma,Pyrazoloacridine,pancreatic,myeloid,Topoisomerase,PD115934
Pyrazolo[3,4,5-kl]acridine-2(6H)-propanamine, 9-methoxy-N,N-dimethyl-5-nitro-
Pyrazoloacridine, 10 mM in DMSO
99009-20-8