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ChemicalBook >> CAS DataBase List >>Spiro[cyclopentane-1,1'(4'H)-naphthalen]-4'-one, 5',8'-dihydroxy-

Spiro[cyclopentane-1,1'(4'H)-naphthalen]-4'-one, 5',8'-dihydroxy-

CAS No.
104260-73-3
Chemical Name:
Spiro[cyclopentane-1,1'(4'H)-naphthalen]-4'-one, 5',8'-dihydroxy-
Synonyms
Collagen-IN-1;Spiro[cyclopentane-1,1'(4'H)-naphthalen]-4'-one, 5',8'-dihydroxy-
CBNumber:
CB012732951
Molecular Formula:
C14H14O3
Molecular Weight:
230.26
MDL Number:
MOL File:
104260-73-3.mol
Last updated:2025-04-28 21:36:36

Spiro[cyclopentane-1,1'(4'H)-naphthalen]-4'-one, 5',8'-dihydroxy- Properties

Melting point 237-238 °C
Boiling point 486.0±45.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
pka 8.40±0.20(Predicted)

Spiro[cyclopentane-1,1'(4'H)-naphthalen]-4'-one, 5',8'-dihydroxy- Chemical Properties,Uses,Production

Uses

Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research[1].

References

[1] Diego Méndez, et al. Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6. Eur J Med Chem. 2020 Apr 15;192:112187. DOI:10.1016/j.ejmech.2020.112187

Spiro[cyclopentane-1,1'(4'H)-naphthalen]-4'-one, 5',8'-dihydroxy- Preparation Products And Raw materials

Raw materials

Preparation Products

Spiro[cyclopentane-1,1'(4'H)-naphthalen]-4'-one, 5',8'-dihydroxy- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19903 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 20701 58

View Lastest Price from Spiro[cyclopentane-1,1'(4'H)-naphthalen]-4'-one, 5',8'-dihydroxy- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Collagen-IN-1 pictures 2025-04-27 Collagen-IN-1
104260-73-3
 US $2785.00-2140.00 / mg 10g TargetMol Chemicals Inc.
  • Collagen-IN-1 pictures
  • Collagen-IN-1
    104260-73-3
  • US $2785.00-2140.00 / mg
  • TargetMol Chemicals Inc.
Spiro[cyclopentane-1,1'(4'H)-naphthalen]-4'-one, 5',8'-dihydroxy- Collagen-IN-1 104260-73-3