N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
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- CAS-Nr.
- 252720-31-3
- Englisch Name:
- N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
- Synonyma:
- 2-Pyridinamine,6-(methylsulfonyl)-;4-(Boc-aMino)piperidine-4-carboxylic Acid;4-(N-Boc-amino)piperidine-4-carboxylic acid;N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID;N-BOC-amino-piperidinyl-1,1-dicarboxylicacid;N-BOC-Amino-piperidinyl-1,1-carboxylic acid,95%;4-(tert-butoxycarbonyl)piperidine-4-carboxylic acid;4-(Boc-amino)piperidine-4-carboxylic acid - [A14679];4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-ca;2-{[(tert-butoxy)carbonyl]aMino}piperidine-1-carboxylic acid
- CBNumber:
- CB8716206
- Summenformel:
- C11H20N2O4
- Molgewicht:
- 244.29
- MOL-Datei:
- 252720-31-3.mol
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N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Eigenschaften
- Siedepunkt:
- 410℃
- Dichte
- 1.18
- Brechungsindex
- 1.4620 (estimate)
- Flammpunkt:
- 202℃
- storage temp.
- 2-8°C(protect from light)
- pka
- 3.36±0.20(Predicted)
- Aussehen
- White to off-white Solid
- InChI
- InChI=1S/C11H20N2O4/c1-10(2,3)17-9(16)13-11(8(14)15)4-6-12-7-5-11/h12H,4-7H2,1-3H3,(H,13,16)(H,14,15)
- InChIKey
- RAENIWWUAIMXSI-UHFFFAOYSA-N
- SMILES
- N1CCC(NC(OC(C)(C)C)=O)(C(O)=O)CC1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
White to off-white crystalline powder
Verwenden
N-Boc-amino-piperidinyl-1,1-carboxylic acid is used in pharmaceutical synthesis.
Synthese
The synthesis of N-BOC-amino-piperidinyl-1,1-carboxylic acid usually starts with piperidine-4-carboxylic acid. Sodium bicarbonate and di-tert-butyl dicarbonate (Boc?O) are added to the reaction system, and the amino protection reaction is carried out in a solvent such as tetrahydrofuran (THF) or 1,4-dioxane. The reaction is stirred at room temperature for several hours until the reaction is completed. Subsequently, the crude product is obtained by steps such as ethyl acetate extraction, pH adjustment of the aqueous phase, drying of the organic phase and reduced pressure concentration, and then purified by column chromatography using a mixed solvent of ethyl acetate and n-hexane as an eluent to finally obtain a high-purity target compound.
N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 127)Lieferanten
252720-31-3()Verwandte Suche:
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- N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
- N-(TERT-BUTOXYCARBONYL)-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
- N-BOC-Amino-piperidinyl-1,1-carboxylic acid,95%
- 4-(tert-butoxycarbonyl)piperidine-4-carboxylic acid
- 4-(Boc-aMino)piperidine-4-carboxylic Acid
- 2-{[(tert-butoxy)carbonyl]aMino}piperidine-1-carboxylic acid
- 4-[[(tert-butoxyl)carbonyl]amino]-4-piperidinecarboxylic acid
- 4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-carboxylic acid
- 4-(N-Boc-amino)piperidine-4-carboxylic acid
- 4-Piperidinecarboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-
- 4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidin-1-ium-4-carboxylate
- 2-Pyridinamine,6-(methylsulfonyl)-
- 4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-ca
- 4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-carboxylicaci
- N-BOC-amino-piperidinyl-1,1-dicarboxylicacid
- 4-(Boc-amino)piperidine-4-carboxylic acid - [A14679]
- 252720-31-3
